Roberto Ripa

Resilience and restoration from fasting-refeeding mediated by a nutrient-regulated linker histone

The paper shows that hil-1/H1-0, a nutrient-regulated linker histone, mediates resilience and restoration during fasting-refeeding in C. elegans and human cells.

Loss of killifish cGAS/STING function attenuates cellular senescence and age-related signatures but does not extend organismal life span

This study shows that knocking out the cGAS/STING pathway in killifish reduces age-related cellular changes and inflammation but does not extend lifespan.

Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology

The paper uses FUCCI technology to study cell cycle dynamics during diapause entry and exit in annual killifish embryos, revealing coordinated cellular changes during quiescent states.

MicroRNA miR-29 controls a compensatory response to limit neuronal iron accumulation during adult life and aging

This study shows miR-29 regulates iron homeostasis in the brain by reducing iron uptake, preventing excessive accumulation and age-related damage.

MicroRNAs provide the first evidence of genetic link between diapause and aging in vertebrates

The paper identifies miRNAs that regulate both diapause and aging in killifish, showing overlapping genetic networks between these processes in vertebrates.