Mario Baumgart

This study develops epigenetic clocks and lifespan predictors for the killifish Nothobranchius furzeri using DNA methylation data, showing high accuracy in age and lifespan estimation.

The paper shows that aging in killifish brains reduces basic amino acid-rich proteins through translation pausing, not transcription or proteasome issues, revealing a vulnerability in nucleic-acid protein biogenesis.

The paper develops a deep learning model called SA-DNN to create an ultraprecise transcriptomic aging clock in the short-lived fish N. furzeri and translates it to human aging with 3-year accuracy.

This study shows that reduced proteasome activity in aging brains leads to ribosome stoichiometry loss and aggregation, increasing mortality risk in killifish.

The paper shows that in juvenile killifish, accelerated brain growth is driven by a second type of progenitors rather than increased radial glia activity.

This study investigates how the hormetic effects of rotenone on lifespan and transcriptome vary with age in a vertebrate species.

The paper presents a comprehensive miRNA and ncRNA catalogue for the short-lived fish Nothobranchius furzeri and compares it to other fish species.

This study shows miR-29 regulates iron homeostasis in the brain by reducing iron uptake, preventing excessive accumulation and age-related damage.

The paper identifies miRNAs that regulate both diapause and aging in killifish, showing overlapping genetic networks between these processes in vertebrates.