Author

Nicole Easo

NYU Langone HealthORCID 0000-0002-9919-3695Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Organism:mouse· 1 Research Focus:variant calling· 1 Organism:yeast· 1

Frequent Co-Authors

Jef D. BoekeiD· 2 shared Ally Moyer· 1 shared Anthony D’Amato· 1 shared Anthony Staiti· 1 shared Antonio Spina· 1 shared Arden Snee· 1 shared Ardeshir Kianercy· 1 shared Brendan R. CamellatoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Jef D. BoekeORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita, Michael J. Shen, LESLIE ANN MITCHELL, Hikaru Kurasawa, Evgenii Lobzaev, Viola Fanfani, Max A. B. Haase, Xiaoji Sun, Qingwen Jiang, Gregory W. Goldberg, David M. Ichikawa, Stephanie L. Lauer, Laura H. McCulloch, , Jef D. Boeke

This paper synthesizes the largest eukaryotic yeast chromosome, synIV, and investigates how its 3D structure affects gene regulation and transcription.

Molecular Cell · Nov 8, 2023Peer-reviewedSynthetic Biology

Synthetic genomic reconstitution reveals principles of mammalian Hox cluster regulation

Sudarshan Pinglay, Milica Bulajić, Dylan P. Rahe, Emily Huang, Ran Brosh, Sergei V. German, John A. Cadley, Lila Rieber, Nicole Easo, Shaun Mahony, Matthew T. Maurano, Liam J. Holt, Esteban O. Mazzoni, Jef D. Boeke

The paper uses synthetic genomic reconstitution to study Hox cluster regulation, finding that distal enhancers are required for full transcriptional output while chromatin remodeling can occur without them.

bioRxiv · Jul 7, 2021 · PreprintSynthetic Biology