The paper conducts a multi-ancestry, trans-generational GWAS meta-analysis of gestational diabetes and glycemic traits, identifying novel loci and highlighting limited pregnancy-specific genetic effects.

Nature Communications · Jun 1, 2026Peer-reviewedGenetic & Genomic Medicine

Genetic effects on the timing of parturition and links to fetal birth weight

Pol Solé-Navais, Christopher J. Flatley, Valgerður Steinthórsdóttir, Marc Vaudel, Julius Juodakis, Jing Chen, Triin Laisk, Abigail Leavitt LaBella, David Westergaard, Jonas Bačelis, Ben Michael Brumpton, Line Skotte, Maria Carolina Borges, Øyvind Helgeland, Anubha Mahajan, , Bo Jacobsson

This study identifies genetic loci associated with gestational duration and preterm delivery, showing maternal and fetal genetic effects and antagonistic pleiotropy with birth weight.

Nature Genetics · Apr 1, 2023Peer-reviewedGenetic & Genomic Medicine

Meta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills.

Doretta Caramaschi, Alexander Neumann, Andrés Cárdenas, Gwen N. Tindula, Silvia Alemany, Lea Zillich, Giancarlo Pesce, Jari M. T. Lahti, Alexandra Havdahl, Rosa H. Mulder, Janine F. Felix, Henning W. Tiemeier, Lea Sirignano, Josef Frank, Stephanie H. Witt, , Gemma C. Sharp

This study examines DNA methylation at birth and its association with childhood cognitive skills, finding weak single CpG site associations and one region near DUSP22 linked to non-verbal cognition.

Molecular Psychiatry · Feb 10, 2022Peer-reviewedDevelopmental Biology