Author

Annette Seibt

Düsseldorf University Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Diran Agaid HerebianiD· 2 shared Felix DistelmaieriD· 2 shared Agnieszka Rybak‐WolfiD· 1 shared Alessandro PrigioneiD· 1 shared Andrea AlfieriiD· 1 shared Andrea GottingeriD· 1 shared Andrea MatteviiD· 1 shared Andrea Rossi· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Diran Agaid HerebianORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

L-2-hydroxyglutarate recycling is linked to coenzyme Q biosynthesis

Marco Malatesta, Andrea Gottinger, Callum R. Nicoll, Diran Agaid Herebian, Demetra Mattiroli, Domiziana Cecchini, Annette Seibt, Andrea Alfieri, Felix Distelmaier, Andrea Mattevi

The paper identifies L2HGDH as a component of the COQ metabolon, linking L-2-hydroxyglutarate recycling to coenzyme Q biosynthesis and showing its role in maintaining biosynthetic intermediates.

bioRxiv · Jul 16, 2026 · PreprintBiochemistry

Deep learning-driven neuromorphogenesis screenings identify repurposable drugs for mitochondrial disease

Carmen Menacho, Satoshi Okawa, Iris Álvarez‐Merz, Annika Wittich, Mikel Muñoz‐Oreja, Paweł Lisowski, Tancredi Massimo Pentimalli, Agnieszka Rybak‐Wolf, Gizem Inak, Shiri Zakin, Mathuravani A. Thevandavakkam, Laura Petersilie, Andrea Zaliani, Barbara Mlody, Annette Seibt, , Alessandro Prigione

The paper identifies repurposable drugs for mitochondrial disease by using deep learning to screen for compounds that improve neuronal commitment and neurogenesis in Leigh syndrome organoids.

bioRxiv · Jul 8, 2024 · PreprintNeuroscience