Author

Femke M. Feringa

Amsterdam NeuroscienceORCID 0000-0002-6003-4048Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:database / resource· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Rik van der KantiD· 2 shared Adrian M. IsaacsiD· 1 shared Alessandro Ori‬‬iD· 1 shared Alexander J. CammackiD· 1 shared Alison D. Do· 1 shared Ashling GibliniD· 1 shared Boudewijn M.T. BurgeringiD· 1 shared Christina E. ToomeyiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Rik van der KantORCID

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Author profile →

3 papers

Recent·Most cited

Protective ApoE variants support neuronal function by extracting peroxidated lipids

Isha Ralhan, Alison D. Do, Ju-Young Bae, Femke M. Feringa, Wendy Cai, Jinlan Chang, Kennedi Chik, Nathanael Y.J. Lee, Christopher J. Gerry, Rik van der Kant, Jesse Jackson, Emily L. Ricq, Maria S. Ioannou

The paper shows ApoE2 and ApoE3Ch variants protect neurons by removing toxic peroxidated lipids, while ApoE4 worsens lipid-induced damage in rodent models.

Neuron · Dec 2, 2025Peer-reviewedNeuroscience

The Neurolipid Atlas: a lipidomics resource for neurodegenerative diseases uncovers cholesterol as a regulator of astrocyte reactivity impaired by ApoE4

Femke M. Feringa, Sascha Koppes-den Hertog, Lian Y. Wang, Rico J. E. Derks, Iris Daphne Kruijff, Lena Erlebach, Jorin Heijneman, Ricardo Miramontes, Nadine Pömpner, Niek Blomberg, Damien Olivier‐Jimenez, Lill Eva Johansen, Alexander J. Cammack, Ashling Giblin, Christina E. Toomey, , Rik van der Kant

The paper introduces the Neurolipid Atlas, a lipidomics resource for neurodegenerative diseases, revealing that ApoE4 impairs astrocyte reactivity by promoting cholesterol ester accumulation.

Nature Metabolism · Sep 22, 2025Peer-reviewedNeuroscience

A FOXO-dependent replication checkpoint restricts proliferation of damaged cells

Marten Hornsveld, Femke M. Feringa, Lenno Krenning, Jeroen van den Berg, Lydia M.M. Smits, Nguyen BT Nguyen, Maria J. Rodríguez Colman, Tobias B. Dansen, René H. Medema, Boudewijn M.T. Burgering

The paper identifies a FOXO-dependent mechanism that restricts proliferation of cells with mild replication stress by promoting premature activation of APC/CCDH1.

Cell Reports · Jan 1, 2021Peer-reviewedMolecular Biology