Author

Joshua Proehl

The University of Texas at San Antonio Health Science CenterORCID 0000-0003-2685-1682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Cameron C. DurfeeiD· 3 shared Reuben S. HarrisiD· 3 shared Xingyu LiuiD· 3 shared Allen J. YorkiD· 2 shared Benjamin Troness· 2 shared Emilia Barreto-DurániD· 2 shared Harshita B. GuptaiD· 2 shared Nuri A. TemiziD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Cameron C. DurfeeORCID

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3 papers

Recent·Most cited

Cancer BiologyJournal of Clinical and Translational SciencePeer-reviewedApr 1, 2026

Murine models for triple-negative breast cancer with differential responsiveness to immunotherapy

Thomas J. Kalantzakos, Yufan Zhou, Xingyu Liu…·Reuben S. Harris

The paper develops two murine TNBC models with differing immunotherapy responses for studying treatment mechanisms and therapies.

DOI 10.1080/29947448.2026.2664260

mouseexperimental assay

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MicrobiologyJournal of VirologyPeer-reviewedFeb 11, 2026

Mus Musculus papillomavirus MmuPV1 resists restriction by human APOBEC3B

Xingyu Liu, Andrea Bilger, Denis Lee…·Reuben S. Harris

This study shows human APOBEC3B does not restrict murine papillomavirus MmuPV1 replication in cellulo or in vivo, suggesting papillomaviruses have evolved mechanisms to evade this antiviral factor.

DOI 10.1128/jvi.01922-25

mousegenetic perturbation / CRISPR

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Cancer BiologybioRxivPreprintJan 18, 2025

Carcinogen-induced DNA adducts amplify APOBEC mutagenesis through nucleotide excision repair

Cameron C. Durfee, Bojana Stefanovska, Rongjie Wu…·Reuben S. Harris

This study shows that carcinogen-induced DNA adducts enhance APOBEC3B-mediated mutagenesis, leading to increased mutation rates in cancer genomes.

4 citations

humanyeast

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