Pawel Licznerski

The paper develops a floxed Gabbr2 mouse model that recapitulates the phenotype of global Gabbr2 knockout mice when Cre is expressed, enabling study of GABBR2 loss in specific cell types.

This paper shows that renalase activates mitochondrial leak metabolism to enhance protein synthesis and protect cells from stress and injury.

The paper shows that Slack channel activation moves FMRP/CYFIP1 from eIF4E to the channel, releasing eIF4E and stimulating translation of β-actin mRNA and cortical β-actin.

This study shows that depletion of PFC GFAP+ astroglia induces anhedonia-like behavior, while their activation reverses stress-induced anhedonia, highlighting their role in depression.