Emmanuel Derivery

This study shows that mTOR signalling, not clock gene rhythms, drives daily physiological variations in mammals and plants.

The paper identifies tubulins in Asgard archaea and shows they form mini-microtubules with eukaryotic-like properties, suggesting an archaeal origin for microtubules.

The paper introduces a multispectral imaging approach for live-cell imaging, enabling accurate unmixing of low signal-to-noise ratio data at video rates.

The paper designs proteins that bind intrinsically disordered regions with high affinity and specificity across diverse targets.

This paper designs a tunable protein filament that assembles in response to a peptide ligand and demonstrates its polarized growth and nucleation mechanisms.

The paper identifies a shared polymerisation switch mechanism in cytomotive actins and tubulins that ensures filament stability and functional dynamics.

The paper designs binary 2D protein co-assemblies that form ordered, biologically active materials with potential therapeutic applications.

This study shows that cerebral organoids cultured at the air-liquid interface form functional nerve tracts with diverse morphologies and connectivity.