Shaun G. Bevers

U1 snRNP and RNA polymerase II interaction is predominantly mediated by Prp40 rather than U1-70K in yeast

The paper investigates the interaction between U1 snRNP and RNA polymerase II in yeast, finding that Prp40, not U1-70K, mediates this interaction, contrasting with the human system.

Mitotic kinase regulation of DNA replication forks

This study shows that mitotic kinases regulate DNA replication forks in budding yeast by phosphorylating replication proteins, affecting fork speed and strand initiation.

A population-scale red blood cell proteome reveals genetically encoded aging clocks predictive of hemolysis and blood donor activity

This paper characterizes the RBC proteome across 13,091 donors, identifies genetic regulators of molecular aging, and shows that aging clocks predict hemolysis, transfusion outcomes, and donor activity.

Red Blood Cells Serve as a Primary Glucose Sink to Improve Glucose Tolerance at Altitude

This study shows that red blood cells act as a primary glucose sink under hypoxia, improving glucose tolerance and offering therapeutic potential for diabetes.

Deep Red Blood Cell Proteome Defines the Band 3 N-Terminus Interactome as a Regulator of Hypoxic Adaptation via BLVRB-Dependent S-Nitroso Transfer

The paper defines the Band 3 N-terminus interactome in red blood cells, revealing its role in hypoxic adaptation through BLVRB-dependent S-nitroso transfer and metabolic remodeling.

Caffeine Impairs Red Blood Cell Storage Quality by Dual Inhibition of ADORA2b Signaling and G6PD Activity

Caffeine consumption and ADORA2b genetic variants impair RBC metabolism and transfusion outcomes through dual mechanisms, highlighting a modifiable interaction for precision transfusion strategies.

Binding of Monomeric and Polymeric Alzheimers Aβ peptides to Exosomes

The paper investigates the binding of Alzheimer's Aβ peptides to exosomes using ITC, finding specific interactions that suggest exosomes as a significant reservoir of these peptides in plasma.