Marie-Anaïs Locquet

This study shows that inhibiting mSWI/SNF complexes enhances the effectiveness of KRAS inhibitors in lung cancers by reversing epithelial-mesenchymal transition resistance.

This paper develops cyclin A/B macrocyclic inhibitors that induce apoptosis in cancers with high E2F activity by blocking RxL-mediated interactions, showing efficacy in SCLC models.

This study shows that in Caspase-8 deficient neuroblastoma cells, TLR3 activation leads to lysosomal cell death instead of apoptosis.