Author

Raymond B. Birge

Rutgers New Jersey Medical SchoolORCID 0000-0002-0721-4672Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Varsha GadiyariD· 3 shared Christopher VarsanyiiD· 2 shared Ahmed AquibiD· 1 shared Alok Kumar ChoudharyiD· 1 shared Chaoyang XueiD· 1 shared Daniele VecchioiD· 1 shared David C. CalianeseiD· 1 shared Eun‐Ah SungiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

Varsha GadiyarORCID

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3 papers

Recent·Most cited

Cardiomyocyte-derived Wnt5a drives doxorubicin-induced cardiomyopathy by amplifying cellular senescence

Eun‐Ah Sung, Peiyong Zhai, Soichiro Ikeda, Masato Matsushita, Koichiro Takayama, Takuma Takada, Nadezhda Fefelova, Lai‐Hua Xie, Ghassan Yehia, Peter J. Romanienko, Varsha Gadiyar, Raymond B. Birge, Daniele Vecchio, Maurizio Forte, Valentina Valenti, , Junichi Sadoshima

This study identifies Wnt5a as a driver of doxorubicin-induced cardiomyopathy by amplifying cellular senescence through a Wnt5a-Fzd2 feed-forward axis.

bioRxiv · Aug 6, 2026 · PreprintCell Biology

Lipid Flippase Mediated Membrane Asymmetry Governs Extracellular Vesicles Biogenesis and Host Interactions in Cryptococcus neoformans

Siddhi Pawar, Yu Zhnag, Christopher Varsanyi, Varsha Gadiyar, Samantha L. Avina, Raymond B. Birge, Chaoyang Xue

This study shows that Cdc50, a lipid flippase regulatory subunit in Cryptococcus neoformans, controls membrane lipid homeostasis, extracellular vesicle biogenesis, and macrophage interactions, with loss of Cdc50 increasing phagocytosis and susceptibility to macrophage killing.

bioRxiv · Jun 13, 2026 · PreprintMicrobiology

Phosphatidylserine (PS)-targeting chimeric Interferon (IFN) fusion proteins for anti-tumor applications

Varsha Gadiyar, Viralkumar Davra, Rachael Pulica, Trevor Frederick, Christopher Varsanyi, Ahmed Aquib, Ziren Wang, Smirnov Sv, Samhita Bapat, David C. Calianese, Alok Kumar Choudhary, Sergei V. Kotenko, Raymond B. Birge

This paper develops PS-targeting chimeric IFN fusion proteins that enhance anti-tumor activities by combining IFN-β and IFN-λ with the PS-binding Gas6 domain.

bioRxiv · Jan 24, 2025 · PreprintCancer Biology