Thoralf Opitz

This study evaluates photopharmacology agents in human and mouse brain tissue to control epilepsy, finding that caged propofol suppresses epileptiform activity across species.

This study identifies region-specific spreading depolarization as a key factor in post-ictal behavioral abnormalities in epilepsy using mouse and human data.

The paper shows that astrocytic signaling via endocannabinoid receptors modulates dendritic integration in hippocampal pyramidal cells, enhancing spatial learning through frequency-dependent feedback.

This study identifies SLK as critical for dendritic complexity and inhibitory synapse maintenance in neurons, with implications for human cortical malformations.

The paper shows that unspecific expression in Cre-driver lines can lead to large functional effects, using SST-Cre mice to demonstrate excitatory current in non-target cells.