Author

William A. Harris

University of CambridgeORCID 0000-0002-9995-8096Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Asha Dwivedy· 2 shared Christine E. HoltiD· 2 shared Clemens F. KaminskiiD· 2 shared Julie Qiaojin LiniD· 2 shared Max KoppersiD· 2 shared Roberta Cagnetta· 2 shared Toshiaki ShigeokaiD· 2 shared Afnan Azizi· 1 shared

Activity by Year

2019-2019 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersNeuroscience

Asha Dwivedy

Mutual co-authors in cluster

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3 papers

Recent·Most cited

On-site ribosome remodeling by locally synthesized ribosomal proteins in axons

Toshiaki Shigeoka, Max Koppers, Hovy Ho‐Wai Wong, Julie Qiaojin Lin, Roberta Cagnetta, Asha Dwivedy, Janaina De Freitas Nascimento, Francesca W. van Tartwijk, Florian Ströhl, Jean-Michel Cioni, Julia Schaeffer, Mark Carrington, Clemens F. Kaminski, Hosung Jung, William A. Harris, Christine E. Holt

The paper shows that ribosomal proteins are synthesized locally in axons and incorporated into ribosomes in a nucleolus-independent manner, regulated by a novel RNA motif.

Cell Reports · Dec 1, 2019Peer-reviewedNeuroscience

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

Max Koppers, Roberta Cagnetta, Toshiaki Shigeoka, Lucia C. S. Wunderlich, Pedro P. Vallejo Ramirez, Julie Qiaojin Lin, Sixian Zhao, Maximilian AH Jakobs, Asha Dwivedy, Michael S. Minett, Anaïs Bellon, Clemens F. Kaminski, William A. Harris, John G Flanagan, Christine E. Holt

The paper shows that receptor-ribosome coupling enables selective mRNA translation in axons in response to guidance cues, with receptor-specific interactomes mediating this process.

eLife · Nov 20, 2019Peer-reviewedDevelopmental Biology

Interkinetic nuclear migration in the zebrafish retina as a diffusive process

Afnan Azizi, Anne Herrmann, Yinan Wan, Salvador J. R. P. Buse, Philipp Keller, Raymond E. Goldstein, William A. Harris

The paper uses imaging to analyze nuclear migration in zebrafish retinas and models it as a diffusive process influenced by nuclear concentration gradients.

bioRxiv · Mar 7, 2019 · PreprintDevelopmental Biology