Valérie Borde

This study identifies HEIP1 as a master regulator of crossover formation in mouse meiosis by orchestrating the recruitment of pro-crossover proteins.

This study identifies RPA as a direct interactor of Mer3/HFM1 helicase, showing its role in enhancing helicase processivity and crossover formation during meiosis.

This paper investigates how Tel1 interacts with Xrs2 to regulate meiotic DNA break interference and the DNA damage checkpoint in yeast.

The paper shows that absence of Red1 and Hop1 recruitment prevents meiotic recombination on a chromosome arm containing the sex locus in Lachancea kluyveri, affecting genome evolution and fitness.

This paper shows Zip4 directly interacts with Ecm11 to couple crossover formation to synaptonemal complex assembly, preventing excess crossovers.

The paper shows that the Pif1 helicase is inhibited by the Mer3-MutLβ complex during meiotic recombination, limiting gene conversion tract length.

The paper identifies the role of the MutLγ-Exo1 complex in meiotic crossover formation by showing Exo1 recruits Cdc5 to activate MutLγ and highlights its spatial regulation near DSB hotspots.

This study shows BLM promotes Homologous Recombination at DSBs in active chromatin but switches to Break-Induced Replication when R-loop dissolution is impaired, reducing cell viability.

This study identifies distinct regions in the Zip1 protein that regulate crossover recombination and synapsis in budding yeast, showing their adjacency enables coordination between these processes.

This paper identifies three separable functions of Spp1 in meiotic DSB formation, showing it interacts with Set1 and Mer2 complexes to promote recombination initiation.