Álvaro Pascual‐Leone

Non-Invasive Brain Stimulation Data Analysis Structure (NIBS-DAS): A Template for the Layout, Management, and Analysis of NIBS Data

The paper introduces NIBS-DAS, a template for structuring, managing, and analyzing NIBS data to improve data sharing and standardization.

Stable Individual Differences Dominate Adult Brain Volume Variation Until Later Life

This study examines how brain volume differences in adults are stable from young adulthood or change with age, using MRI data from 8,311 individuals.

Sensory Entrained TMS (seTMS) enhances motor cortex plasticity

This study shows that sensory entrained iTBS (se-iTBS) significantly enhances motor-evoked potentials compared to standard iTBS, with effects lasting at least 30 minutes.

Sensory Entrained TMS (seTMS) enhances motor cortex excitability

This study introduces seTMS, a method that enhances motor cortex excitability by synchronizing TMS pulses with sensorimotor alpha rhythms using musical rhythms, resulting in larger motor-evoked potentials.

Vulnerability to memory decline in aging. A mega-analysis of structural brain change.

This study investigates the relationship between brain atrophy and memory decline in aging using longitudinal data, finding a nonlinear association that intensifies with age and is influenced by APOE ε4 carriership.

Genome-wide QTL mapping across three tissues highlights several Alzheimer's and Parkinson's disease loci potentially acting via DNA methylation

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

Resting-state EEG signatures of Alzheimer's disease are driven by periodic but not aperiodic changes

The paper investigates whether Alzheimer's disease EEG changes are due to periodic or aperiodic signal alterations, finding they are purely periodic.

Reliability of resting-state EEG modulation by continuous and intermittent theta burst stimulation of the primary motor cortex: A sham-controlled study

This study examines the reliability of resting-state EEG modulation by cTBS and iTBS on the primary motor cortex, finding no significant group-level effects and low-to-moderate reliability across sessions.

Non-invasive temporal interference electrical stimulation of the human hippocampus

This study validates non-invasive temporal interference stimulation of the human hippocampus, showing it can modulate activity and improve episodic memory.

Blinding efficacy and adverse events following repeated transcranial alternating current, direct current, and random noise stimulation.

This study evaluates adverse events and blinding efficacy of repeated transcranial electrical stimulation in 1,019 participants across four sites, finding that blinding was less effective for tDCS and tACS than tRNS.

Phase-amplitude coupling and phase synchronization between medial temporal, frontal and posterior brain regions support episodic autobiographical memory recall

The paper investigates inter-regional brain interactions during episodic memory recall using EEG and finds distinct phase-amplitude coupling and synchronization patterns in specific brain networks.

Towards the identification and optimization of the "dose-response" relationship of transcranial direct current stimulation

This paper investigates how variations in electric field distribution from tDCS affect cognitive-motor outcomes in older adults and shows that optimized multichannel montages can improve targeting and reduce variability.

Large-scale analysis of interindividual variability in single and paired-pulse TMS data: results from the 'Big TMS Data Collaboration'

This study analyzes interindividual variability in single and paired-pulse TMS data across 35 studies, identifying factors that predict TMS responses and proposing standardization recommendations.

Greater TMS-evoked frontoparietal effective connectivity is correlated with better cognitive performance

This study finds that TMS-evoked propagation of neural signals in frontoparietal regions correlates with better global cognitive performance, but not local activity.

Realistic modeling of ephaptic fields in the human brain

This study models ephaptic fields in the human brain across aging, finding they decrease with age and follow gyrification patterns, with higher involvement in sensorimotor and medial regions.

Multifocal tDCS modulates resting-state functional connectivity in older adults depending on induced electric field and baseline connectivity

This study shows that multifocal tDCS modulates resting-state connectivity in older adults, with effects dependent on electric field distribution and baseline connectivity.