Author

Elena G. Assad

Harvard UniversityORCID 0009-0004-0487-9064Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:statistical model· 3 Assay:ATAC-seq· 2 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

Eric C. GriffithiD· 4 shared Michael E. GreenbergiD· 4 shared Erin E. DuffyiD· 3 shared Benjamin FinanderiD· 2 shared Brian Thomas KalishiD· 2 shared Lisa TraunmülleriD· 2 shared Naeem S. Pajarillo· 2 shared Sebastian KrüttneriD· 2 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersNeuroscience

Eric C. GriffithORCID

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4 papers

Recent·Most cited

Neuronal activity triggers widespread changes in RNA stability

Erin E. Duffy, Inés Lucía Patop, Shelly Kalaora, Elena G. Assad, Shon A. Koren, Lisa Traunmüller, Sebastian Krüttner, Naeem S. Pajarillo, Benjamin Finander, Zachary Barsdale, Mia M. Macias, Min Yi Feng, João A. Paulo, Eric C. Griffith, Brian Thomas Kalish, , Michael E. Greenberg

The paper shows neuronal activity affects RNA stability, with HuD regulating mRNA abundance and variants linked to neurodevelopmental disorders disrupting this process.

bioRxiv · Sep 5, 2025 · PreprintNeuroscience

Novel environment exposure drives temporally defined and region-specific chromatin accessibility and gene expression changes in the hippocampus

Lisa Traunmüller, Erin E. Duffy, Hanqing Liu, Stella Sanalidou, Sebastian Krüttner, Elena G. Assad, Senmiao Sun, Naeem S. Pajarillo, Nancy Niu, Eric C. Griffith, Michael E. Greenberg

This study identifies cell-type-specific chromatin accessibility and gene expression changes in the hippocampus following novel environment exposure using single-nucleus multiomics and bulk RNA-seq.

Nature Communications · Aug 21, 2025Peer-reviewedNeuroscience

Developmental Dynamics of RNA Translation in the Human Brain

Erin E. Duffy, Benjamin Finander, GiHun Choi, Ava C. Carter, Iva Pritišanac, Aqsa Alam, Victor A Luria, Amir Karger, William Phu, Maxwell A. Sherman, Elena G. Assad, Naomi Pajarillo, Alexandra Khitun, Elizabeth Erin Crouch, Sanika Ganesh, , Michael E. Greenberg

This study maps RNA translation dynamics in the human brain using ribosome profiling, identifying thousands of novel translation events and brain-specific microproteins linked to schizophrenia.

Nature Neuroscience · Sep 28, 2022Peer-reviewedNeuroscience

PESCA: A scalable platform for the development of cell-type-specific viral drivers

Siniša Hrvatin, Christopher P. Tzeng, M. Aurel Nagy, Hume Stroud, Charalampia Koutsioumpa, Oren F. Wilcox, Elena G. Assad, Jonathan Green, Christopher D. Harvey, Eric C. Griffith, Michael E. Greenberg

PESCA identifies cell-type-specific enhancers using ATAC- and single-cell RNA-sequencing to generate viral reagents for targeted gene manipulation in mammalian cells.

bioRxiv · Sep 4, 2019 · PreprintNeuroscience