Author
Harvard UniversityORCID 0009-0007-9309-5481Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jenny A. Klein, Suraj Upadhya, Anna J. Nathanson…·Lindy E. Barrett
This study identifies aberrant chromatin remodeling in Trisomy 21 NPCs that impairs neurogenesis and shows that PRC2 inhibition can partially restore neurogenic potential.
Zuen Ren, Tiziano Bernasocchi, Kiran Kurmi…·Leif William Ellisen
This study identifies SIRT5-induced metabolic changes as a driver of chemoresistance in TNBC and reveals ATR checkpoint dependence as a therapeutic vulnerability.
Joanna A. Vuille, Cem Tanrıöver, Ezgi Antmen…·Daniel A. Haber
The paper identifies HECTD4 as a tumor and metastasis suppressor that targets COX-2 for degradation, with COX-2 stabilization driving pro-tumorigenic effects in breast cancer.
Mutsumi Kobayashi, Misato Kobayashi, Johannes Kreuzer…·Toshi Shioda
The paper identifies LTR5_Hs viral proteins and virus-like particles in hPGCLCs, showing their activation during early germ cell development and suppression upon gonadal anlagen settlement.