rat

This paper introduces a fibrous optofluidic probe for measuring blood oxygenation and flow velocity in vessels, demonstrating its use in rabbit and canine models.

This paper introduces [18F]GPR39 2.1, a PET radiotracer for noninvasive imaging of GPR39, showing high specificity and sensitivity in vivo.

This study shows that dual inhibition of MLK3 and LRRK2 with URMC-099 reduces PD pathology and motor deficits in an AAV-haSyn rat model.

This study identifies middle ear dysfunction as the primary cause of residual hearing loss in chronically implanted guinea pigs, suggesting a conductive mechanism.

This study evaluates AAV9-mediated SLC9A6 gene replacement in shaker rats, showing early treatment preserves cerebellar structure and motor function, while later treatment has diminishing effects.

This study investigates sex-specific effects of hypertension on cerebral hemodynamics and memory, finding that MR antagonism improves perfusion and memory in female rats but not males.

This study examines how chronic hypertension and sex affect vascular density in different regions of the hippocampus in rats, finding sex-specific changes in vascular structure.

The paper examines axon survival in chronically demyelinated taiep rats and finds that small diameter axons can survive for months with increased glial support.

This study develops a cross-species framework linking collagen structure to mechanical vulnerability in intervertebral discs using multiscale imaging and modeling.

This paper introduces NORIGAMI, a multi-omics pipeline that combines imaging and deep learning to analyze kidney aging, revealing age-related structural and molecular changes.

This study investigates how L-DOPA-induced dyskinesia (LID) relates to microstructural changes in brain circuits, finding brainwide alterations beyond the nigrostriatal system.

This study examines how physical exercise affects osteocyte lacunar morphology and orientation around bioresorbable implants in rats, showing increased lacunar size and altered orientation with exercise.

This study evaluates electrically enhanced intraperitoneal drug delivery using nanoparticles and fluorescence lifetime imaging microscopy to track drug penetration and intracellular release.

This study validates arthroscopic Raman spectroscopy for quantifying TMJ tissue composition and mechanical properties, showing strong correlations with indentation and tensile modulus.

OocystMeter automates oocyst counting and sizing in mosquito midguts, revealing clustered spatial patterns in malaria infections.

This study uses functional ultrasound imaging to map brain and spinal cord activity during micturition in rats, revealing region-specific hemodynamic responses and decoding bladder pressure dynamics.

This study uses ultrasound to detect venous gas emboli and tissue gas in rats after decompression, finding a correlation between gas emboli severity and decompression risk.

This study shows that grooming movements in rhesus macaques are adapted from feeding movements, with similar hand motions used for both tasks.

golgi provides an open-source platform for modeling peripheral nerve stimulation, enabling image-to-recruitment analysis with a graphical interface and reproducible results.

The paper validates 2D histology for representing axon radius distributions and conduction velocities using 3D reconstructions of rat axons and applies this to human data.

Focal transcranial magnetic stimulation of the rat anterior cingulate cortex reduced relapse-like behavior and restored corticostriatal connectivity during opioid abstinence.

EGFR-family ligand mRNAs shift in failing human hearts; NRG1 and EGF drive distinct, differently ERBB2-dependent transcriptional programmes in rat cardiomyocytes; afatinib blunts mouse angiotensin II hypertrophy but worsens fibrosis.

This study identifies a motor-sensory convergence point during object approach in rats, showing it enables robust object detection through dynamic sensory-motor interactions.

This study examines neural activity in the medial amygdala and bed nucleus of the stria terminalis in male rats during social and sexual interactions, revealing distinct response patterns to olfactory and tactile cues based on experience.

This study shows that lesions to the retrosplenial cortex in rats do not significantly affect social approach dynamics during interactions with a social stimulus.

This study establishes normative green autofluorescence (GAF) values in rhesus macaques across different retinal regions and links GAF to age, intraocular pressure, and retinal structure.

This study evaluates [18F]Itareparib as a PARP1-selective radioligand for PET imaging of gliomas, showing brain penetration and specific tumor uptake in rat models and nonhuman primates.

The paper compares left ventricular phenotypes across humans, chimpanzees, and macaques to identify structural and functional traits associated with higher stroke volume in humans.

This study shows maternal obesity accelerates cardiomyocyte maturation in offspring, leading to adult heart dysfunction through cytoarchitectural disruption.

This paper introduces a workflow combining 3D-PLI, immunohistochemistry, and Nissl staining to map fiber architecture and cell types in brain sections with high resolution and reduced inter-subject variability.