Pharmaceutical and Antibiotic Environmental Impacts

Genome-resolved metagenomics reveals the potential for selection for antibiotic resistance due to metal pollution in soil microbial communities near a copper-nickel mine site in Botswana

This study uses genome-resolved metagenomics to show that metal pollution from a copper-nickel mine in Botswana may lead to co-selection of antibiotic resistance genes (ARGs) and metal resistance genes (MRGs) in soil microbial communities.

Dairy manure analysis reveals significant risk of Antibiotic resistance from Extracellular DNA in Manure storage Pit

This study quantifies antibiotic resistance genes and mobile genetic elements in intracellular and extracellular DNA from fresh and stored dairy manure, finding exDNA is enriched in pits and may enhance gene transfer.

Wastewater-impacted Skagerrak Sea microbiomes anaerobically demethylate micropollutants

The paper investigates anaerobic demethylation of methylated micropollutants in Skagerrak Sea sediments, showing bacterial and archaeal pathways for naproxen but recalcitrance for caffeine.

Reduced antibiotic effect of ciprofloxacin on bacteria in the presence of montmorillonite

This study shows that montmorillonite reduces but does not eliminate ciprofloxacin's growth-inhibitory effect on bacteria in soil environments.

Bacterial Membrane Vesicles in Wastewater Disseminate Antibiotic Resistance Genes

This study isolates bacterial membrane vesicles from wastewater and finds they carry antibiotic resistance genes, persist through treatment, and contribute to antimicrobial resistance spread.

Reusable immobilised quaternary ammonium particles reduce microbial and resistome burdens without promoting resistance selection during wastewater post-treatment.

This paper evaluates immobilized BDMDAC particles for wastewater treatment, showing they reduce microbial and ARG burdens without promoting resistance selection.

A Multi-Scale Ecological Approach to Assessing Antimicrobial Resistance in a Freshwater Fish

This study assesses antimicrobial resistance in freshwater fish by integrating molecular measurements with geospatial modeling to identify environmental factors linked to AMR gene distribution.

Ripples of Resistance: Unveiling Antimicrobial Resistance Dynamics Along Switzerland's Aare River

This study tracks antimicrobial resistance gene (ARG) distribution along Switzerland's Aare River, showing increased ARG abundance downstream due to wastewater treatment plant effluents.

Assessment of the household antibiotic resistance gene, virulence factor genes, and pathogen profiles from three global cities

This study examines antibiotic resistance genes, virulence factors, and pathogens in household environments across three global cities, revealing geographic and spatial variations in microbial profiles.

Investigating the distribution of antibiotic resistance genes in relation to bacterial, fungal, and functional diversity in a hay field.

The paper examines how bacterial, fungal, and functional diversity influence the distribution of antibiotic resistance genes in a hay field, finding that clinical ARG diversity is more linked to fungal diversity than bacterial diversity.

Accumulation of ibuprofen in endemic amphipods of Lake Baikal

This study measures ibuprofen accumulation in Lake Baikal amphipods, finding species-specific, seasonal, and size-related variation in contamination.

Urbanisation Reshapes Freshwater Microbiomes: A Systematic Review of Ecological Patterns and Functional Shifts

This paper systematically reviews the impacts of urbanisation on freshwater microbiomes, finding reduced bacterial diversity and increased Proteobacteria, Cyanobacteria, and Coliform bacteria.

Investigating the resistome, taxonomic composition, andmobilome of bacterial communities in hospital wastewaters ofMetro Manila using a shotgun metagenomics approach

This study analyzes antibiotic resistance genes, bacterial communities, and mobile genetic elements in hospital wastewater from Metro Manila using shotgun metagenomics, revealing high abundances of resistance genes and dominant bacterial taxa.

SELECT 2.0: Refined and open access SELection Endpoints in Communities of bacTeria (SELECT) method to determine concentrations of antibiotics that may select for antimicrobial resistance in the environment

This paper refines the SELECT method to predict no effect concentrations for resistance (PNECRs) of 32 antibiotics, aiding environmental risk assessments by ranking antibiotics based on their potential to select for antimicrobial resistance.

Using Hi-C and target capture to monitor plasmid transfer in the barley rhizosphere

This study shows plasmid transfer from manure to soil bacteria in barley rhizosphere, but no long-term persistence, with hosts remaining unidentified due to database limitations.

Micropollutant-driven bacterial adaptation enables resilient pharmaceuticals biodegradation at trace concentrations in biologically treated wastewater.

The paper shows that microbial consortia adapted to pharmaceuticals retain degradation capacity across wide concentration ranges and can be applied to real wastewater treatment.

Marine bacterial resistomes integrate ecological adaptation with anthropogenic amplification: genome-resolved insight along a gradient of human impact

This study quantifies how human impact influences marine bacterial antibiotic resistance genes (ARGs) using genome-resolved metagenomics across different environmental gradients.

Investigating the impact of carbamazepine on tomato plant metabolism using genome-scale metabolic modelling

This study uses genome-scale metabolic modeling to analyze how carbamazepine affects tomato plant metabolism and identifies biostimulants that mitigate its stress effects.

Combined Antibiotic and Herbicide Pollution Accelerates the Horizontal Transfer of Antibiotic Resistance Genes in Coastal Microbial Communities

Soil microbial and plant responses to increasing antibiotic concentration: a case study of five antibiotics

This study examines the effects of five antibiotics on soil microbial communities, antibiotic resistance genes, and plant growth in a controlled greenhouse experiment, finding significant impacts on prokaryotic diversity and plant productivity.

Pharmaceuticals residues lead to enrichment of Human, Animal, and Plant Pathogens in Wastewater

This study shows that common pharmaceuticals increase pathogen abundance and biodiversity in wastewater, posing a biohazard risk.

Extended-Spectrum and Last-Resort β-Lactams Exert Increasing Impacts on Chicken Manure-Derived Copiotrophic Microbiomes and Resistomes

This study examines how beta-lactamase-resistant antibiotics shape microbial communities and resistance profiles in chicken manure-derived copiotrophic microbiomes compared to earlier beta-lactams and antibiotic-free controls.

Distribution of antibiotic resistance genes across contrasted tropical agroecosystems in Reunion Island

This study assesses antibiotic resistance genes and residues in tropical agroecosystems, finding high ARG prevalence in amended soils and manure, with potential human exposure through food chains.

Protein engineering of a genetically encoded biosensor for wastewater detection of profen NSAIDs

The paper engineers a genetically encoded biosensor, PYRNSAID, to detect profen NSAIDs in wastewater with nanomolar sensitivity and demonstrates its functionality in simulated wastewater matrices.

ARGfore: A multivariate framework for forecasting antibiotic resistance gene abundances using time-series metagenomic datasets

ARGfore forecasts antibiotic resistance gene abundances from time-series metagenomic data, outperforming standard methods with lower error and better efficiency.

Antimicrobial resistant bacteria in wastewater-irrigated Mexican soils and transfer of resistant bacteria from irrigated soils to cilantro plants

This study evaluates the impact of wastewater treatment on antimicrobial resistant bacteria in soils and their transfer to cilantro plants in Mexico, finding that treatment does not reduce resistant bacteria abundance.

Impacts of wastewater treatment and the exposome on antibiotic resistance gene dynamics: Insights from Guadeloupe, a French Caribbean Island

This study examines how wastewater treatment plants affect antibiotic resistance gene abundance and pollutant levels in Guadeloupe, finding reduced ARGs but increased mcr-1 and variable antibiotic removal.

Antimicrobial resistance as a signature of soil restoration across a 143-year chronosequence

This study shows that antimicrobial resistance increases with soil restoration age, indicating a mature microbiome rather than degradation.

The role of heavy metals in the co-selection of plasmid-borne metal and antibiotic resistance genes from industrially contaminated sediments.

This study investigates how heavy metal contamination in sediments selects for plasmids carrying both metal and antibiotic resistance genes, showing co-selection through co-resistance mechanisms.

Ribosomal Epistatic Interactions Drive the Emergence of High-Level Streptomycin Resistance in Escherichia coli

This study identifies epistatic interactions among ribosomal mutations that confer high-level streptomycin resistance in E. coli under environmental selection pressures.