Pharmaceutical and Antibiotic Environmental Impacts

Anthropogenic land use exerts selection pressures on the resistome of a wild rodent

The paper analyzes ARGs in wild house mice to show that agricultural land use and livestock exposure increase mobile ARG occurrence.

Revealing the antibiotic resistome in the global hadal trenches by large-scale cultivation and metagenomics

This study investigates antibiotic resistance genes and bacteria in hadal trench sediments using cultivation and metagenomics, finding a pristine reservoir with distinct ARG dynamics and phylogenetic clusters.

Shotgun metagenomics reveals the microbiome and resistome of water harvesting ponds used by Kenyan rural smallholders

The paper uses shotgun metagenomics to analyze Kenyan water harvesting ponds, identifying antibiotic resistance genes and their potential for horizontal transfer.

Impact of biosolids amendment on the soil resistome and microbiome - a greenhouse study

This study examines how biosolids amendment affects soil microbiome, resistome, and pathogens in a greenhouse carrot cultivation experiment, finding increased ARGs and ESKAPE pathogens.

Sulfonamide resistance gene sul4 is hosted by common wastewater sludge bacteria and found in various newly described contexts and hosts including clinically relevant species

This study identifies the sul4 sulfonamide resistance gene in wastewater sludge bacteria and shows its presence in clinically relevant pathogens, highlighting its mobility and potential for horizontal gene transfer.

Grasping the constraints of pure bacterial strains for the complete catabolism of micropollutants: a proteomic and kinetic study

This study investigates the incomplete biotransformation of sulfamethoxazole by a bacterial strain, linking it to proteomic profiles and enzyme activity differences.

Metagenomic Profiling of Drinking Water Microbiomes: Insights into Microbial Diversity and Antimicrobial Resistance

This study uses metagenomic analysis to characterize drinking water microbiomes in an Indian city, identifying core bacterial species and widespread antibiotic resistance genes.

Inferring antibiotic resistance selection in the environment can be confounded by correlations between resistance genes and unrelated functional traits

The paper shows that changes in ARG abundance in environmental studies may be due to community shifts rather than antibiotic selection, using correlations with ribosomal RNA genes.

Struvite fertiliser offers a sustainable solution for recycling of phosphorus for crop growth without altering the soil resistome.

This study evaluates the impact of struvite fertiliser on soil antimicrobial resistance and finds no significant increase in AMR genes or resistant bacteria compared to conventional fertilisers.

Antibiotic resistance genes detected in lichens: insights from Cladonia stellaris

This study detects antibiotic resistance genes in lichens from boreal forests, showing their diversity and potential origins through geographic and microbial association analyses.

Gene flow between environmental and enteric bacteria with environmental coselection for metal and antibiotic resistance genes: A case study

This study identifies gene flow and co-selection for antibiotic and metal resistance genes in industrial sediments and water, highlighting heavy metals as a selective pressure for multidrug resistance.

Plasmids from a complex biome exist as communities

This study sequenced plasmids from wastewater treatment plant effluent and found they exist in communities rather than as isolated entities, with implications for antimicrobial resistance gene spread.

Selective spread of mobile antibiotic resistance genes in wastewater microbiomes driven by the non-antibiotic pharmaceutical carbamazepine

This study shows that carbamazepine promotes the spread of specific antibiotic resistance genes in wastewater microbiomes through horizontal gene transfer and direct selection.

Large-language-model-based antibiotic resistance gene prediction and resistomes mining in cyanobacterial blooms

ESMARG, a large-language-model-based tool, improves antibiotic resistance gene detection in metagenomes and reveals seasonal dynamics and ecological factors in cyanobacterial blooms.

Detection of Antibiotic-resistant Escherichia coli in the Euphrates River, Iraq

This study identifies antibiotic-resistant Escherichia coli in the Euphrates River in Iraq, showing high resistance rates and multidrug resistance linked to environmental pollution.

Freshwater snail faecal metagenomes reveal environmental reservoirs of antimicrobial resistance genes across two continents

This study identifies freshwater snail faeces as environmental reservoirs of antimicrobial resistance genes across multiple countries using metagenomic analysis.

Metagenomic Analysis Reveals Northwest Pacific Ocean as a Reservoir and Evolutionary Hub of Antibiotic Resistance Genes

The paper identifies a hotspot of antibiotic resistance genes in the Northwest Pacific Ocean, showing high abundance and unique resistance mechanisms.

Context-dependent effects of ivermectin residues on dung insects: Interactions with environmental stressors, size, and sex in a sepsid fly (Sepsis neocynipsea)

This study examines how ivermectin residues interact with environmental stressors, size, and sex to affect survival in the sepsid fly Sepsis neocynipsea.

Target-enriched metagenomics-informed qPCR detects rare, potentially dangerous β-lactamase genes in wastewater

This paper introduces a hybrid ARG surveillance method combining target-enriched metagenomics and qPCR to detect rare β-lactamase genes in wastewater.

An integrated meta-omics approach for identifying candidate organic micropollutant degraders in complex microbial communities

The paper identifies candidate organic micropollutant degraders in microbial communities by integrating metagenomics and metatranscriptomics to correlate biotransformation with microbial activity.

Genes on the Move: Exploring the Resistome of Viable Isolates from a First Nation Community in Manitoba

This study analyzes the resistome of bacterial isolates from an oxidation lagoon in a First Nation community, identifying antibiotic resistance genes and mobile genetic elements in wastewater treatment systems.

Compost bacteria as a promising new solution for degradation of diclofenac and related pharmaceuticals for water treatment processes

This study shows thermophilic compost microorganisms can efficiently degrade diclofenac and related pharmaceuticals, outperforming mesophilic microbes in wastewater treatment.

Beach sand beneath our feet: an overlooked reservoir of antibiotic resistance genes and pathogens, revealed by metagenomic evidence from Qingdao's recreational beaches

Regulating oxygen avaibility mitigates oxidative stresses-induced antibiotic resistance gene expression in E. coli under climate warming

This study shows that regulating oxygen availability reduces antibiotic resistance gene expression in E. coli under warming by altering metabolic and oxidative stress responses.

Sequential exposure to anoxic/oxic conditions leads to biotransformation and detoxification of sitagliptin in urban hyporheic zones

This study investigates sitagliptin biotransformation in hyporheic zones under anoxic and oxic conditions, identifying detoxification pathways and transformation products.

Identification of clinical carbapenemases, 478 novel β-lactamases and putative seven new bacterial phyla from wastewater contaminated high arctic fjord sediments.

The paper identifies antibiotic resistance genes, novel β-lactamases, and potential new bacterial phyla in high Arctic fjord sediments impacted by wastewater.

Genotypic Characterization of Virulence and Antibiotic-Heavy Metal Resistance in Enterococcus Strains from Vladivostoks Water Bodies

This study characterizes antibiotic and heavy metal resistance genes in Enterococcus strains from Vladivostok water bodies, revealing co-occurrence patterns and potential genetic linkages.

Metagenomic co-assembly reveals mobile antibiotic resistance genes in airborne microbiomes in the Eastern Mediterranean

The paper identifies mobile antibiotic resistance genes in airborne microbiomes using metagenomic co-assembly, showing their potential for global spread via air masses.

Community-promoted antibiotic resistance genes show increased dissemination among pathogens

The paper investigates how the prevalence of antibiotic resistance genes in human gut and wastewater microbiomes correlates with their dissemination among bacterial pathogens.

The link between antibiotic resistance level and soil physico-chemical properties

This study examines how soil physico-chemical properties correlate with antibiotic resistance gene abundance in agricultural and forest soils, revealing environmental factors influencing AMR spread.