Forensic and Genetic Research

Haplotype sharing provides insights into fine-scale population history and disease in Finland

This study uses haplotype sharing among Finns to reconstruct recent population history and identify regions with increased rare disease variant sharing.

Genetic patterning in Central Eurasia: population history and pigmentation

The paper analyzes genetic variation in Central Eurasia to infer population history and pigmentation patterns, finding convergent evolution in skin pigmentation genes.

Estimating genetic kin relationships in prehistoric populations

The paper develops a tool to estimate genetic kin relationships in prehistoric populations using degraded ancient DNA data, revealing previously unknown family ties.

Reappraising the human mitochondrial DNA recombination dogma

This study provides direct and indirect evidence of frequent mtDNA recombination in humans, challenging the non-recombination dogma and its implications for evolutionary history and disease.

GrigoraSNPs: Optimized HTS DNA Forensic SNP Analysis

GrigoraSNPs optimizes SNP calling in DNA forensics by improving runtime efficiency for high-throughput sequencing data.

Multidimensional Scaling and Relatedness Research

This paper introduces a method combining genetic bootstrapping, multidimensional scaling, and discriminant analysis to classify genetic relationships with high accuracy using identity-by-state data.

Comparison of two ancient DNA extraction protocols for skeletal remains from tropical environments

This study compares two DNA extraction methods for ancient samples from tropical environments, finding Method D better for fragmented DNA recovery.

A set informative multiple autosomal markers for human identification: forensic research and population genetics analysis in a Chinese Xinjiang Hui group

The paper identifies 30 InDel markers for forensic identification and population genetics analysis in the Chinese Xinjiang Hui group, showing high discriminatory power and genetic similarity to Han populations.

Estimation of population divergence times from SNP data and a test for treeness

The paper presents a method to estimate population divergence times from SNP data and tests for treeness in population history using archaic genomes.

Messenger RNA biomarker signatures for forensic body fluid identification revealed by targeted RNA sequencing

The paper develops a targeted RNA sequencing assay to identify forensic body fluids using specific gene markers and demonstrates its sensitivity and specificity in single-source and admixed stains.

New insights from Thailand into the maternal genetic history of Mainland Southeast Asia

The paper analyzes additional mtDNA sequences from Thailand and Laos to explore the genetic history of Tai-Kadai and Sino-Tibetan-speaking populations in Mainland Southeast Asia, finding evidence for both demic diffusion and admixture.

The Beaker Phenomenon And The Genomic Transformation Of Northwest Europe

This study uses ancient DNA data to show that the spread of the Beaker Complex to Britain was primarily due to migration, replacing most Neolithic gene pool and introducing Steppe ancestry.

The Genomic History Of Southeastern Europe

Ancient DNA from 223 people (12,000-500 BCE) reveals a west-east hunter-gatherer cline, largely unadmixed farmers, Caucasus-shifted Aegean farmers, and Balkan steppe ancestry almost 2,000 years early.

Complex genetic patterns in human arise from a simple range-expansion model over continental landmasses

The paper uses simulations and Bayesian methods to show a simple range-expansion model explains much of human genetic diversity.

Patterns of shared signatures of recent positive selection across human populations

The paper identifies shared signatures of recent positive selection across 20 human populations and links them to potential biological mechanisms.

Age distributions of rare lineages reveal recent demographic history and selection

The paper estimates the age of rare alleles using haplotype sharing to infer demographic history and selection pressures in a UK population.

Assessing Runs of Homozygosity: A comparison of SNP Array and Whole Genome Sequence low coverage data

The paper compares Runs of Homozygosity (ROH) detected from SNP array and low coverage whole genome sequence data to establish guidelines for combining datasets.

Insular Celtic population structure and genomic footprints of migration

This paper uses haplotype-based methods to reveal genetic structure in Ireland, showing regional diversity and historical migrations, with implications for genetic association studies.

Inference of Multiple-wave Admixtures by Length Distribution of Ancestral Tracks

The paper introduces MultiWaver, a method to infer multiple-wave admixture histories from ancestral tracks, validated on real datasets.

Contrasting maternal and paternal genetic variation of hunter-gatherer groups in Thailand

The paper analyzes maternal and paternal genetic variation in Thai hunter-gatherer groups, finding distinct haplogroup patterns and suggesting a recent origin for the Mlabri population.

A population phylogenetic view of mitochondrial heteroplasmy

The paper develops a population-genetic framework to model mitochondrial heteroplasmy inheritance and applies it to infer genetic drift and mutation rates during human development.

MITOMIX, an Algorithm to Reconstruct Population Admixture Histories Indicates Ancient European Ancestry of Modern Hungarians

MITOMIX uses a new distance metric to analyze admixture in populations, showing modern Hungarians have mostly European ancestry with minor contributions from conquerors.

Genomics of Mesolithic Scandinavia reveal colonization routes and high-latitude adaptation

The paper analyzes genomic data from Mesolithic Scandinavians to show two colonization routes and genetic adaptations to high-latitude environments.

The maternal genetic history of the Angolan Namib Desert: a key region for understanding the peopling of southern Africa

The paper analyzes maternal genetic structure in Namib Desert populations to evaluate peopling hypotheses, finding strong Bantu influences and endogamous matriclanic systems.

Fast P(RMNE): Fast Forensic DNA Probability of Random Man Not Excluded Calculation

The paper introduces a new formula for efficiently calculating P(RMNE) in DNA mixture analysis to handle larger SNP panels without computational artifacts.

Powerful Inference with the D-statistic on Low-Coverage Whole-Genome Data

The paper improves the D-statistic for detecting ancient admixture by using all reads and error correction, showing better performance at low sequencing depth.

The Plateau Method for Forensic DNA SNP Mixture Deconvolution

The paper introduces the Plateau method to deconvolve DNA mixtures into individual sub-profiles using SNP data without reference profiles, detecting contributors as low as 1/200 in concentration.

The maternal genetic make-up of the Iberian Peninsula between the Neolithic and the Early Bronze Age

The paper analyzes ancient mitochondrial DNA from the Iberian Peninsula to study maternal genetic changes from the Neolithic to the Early Bronze Age, finding regional continuity and distinct population history compared to Central Europe.

How Convincing Is A Matching Y-Chromosome Profile?

The paper proposes a simulation model and software to estimate the number of males with a matching Y-chromosome profile, addressing challenges in forensic DNA evidence evaluation.

Parallel paleogenomic transects reveal complex genetic history of early European farmers

The paper analyzes ancient DNA data from Neolithic and Chalcolithic Europe to study population dynamics and admixture patterns across different regions and time periods.