Wound Healing and Treatments

This paper evaluates a fermented polyherbal formulation's efficacy in reducing burn wound severity caused by multiple-antibiotic-resistant Pseudomonas aeruginosa in a rat model.

This study characterizes the proteomic and microbial composition of wound slough and integrates these with clinical data to predict wound healing outcomes.

This study uses scRNA-seq to analyze infected and uninfected wounds in mice, revealing transcriptional and metabolic changes linked to E. faecalis infection and its impact on wound healing.

This paper introduces a wearable bioelectronic bandage that delivers fluoxetine on-demand to wounds, reducing inflammation and accelerating healing in mice.

This study evaluates an HOCl-producing electrochemical bandage for treating Pseudomonas aeruginosa-infected wounds, showing significant biofilm reduction without impairing wound healing.

The paper compares adipogenesis and immune responses in MRL/MpJ and C57BL/6 mice after injury and material implantation, finding differences in adipose tissue formation and foreign body reactions.

This paper develops a programmable multimodal wearable potentiostat for generating reactive oxygen species to treat biofilm-infected wounds, showing broad-spectrum antimicrobial activity.

This paper develops a fluorescent pH-sensing bandage for diagnosing diabetic foot ulcers by detecting pH changes in wounds.

This study uses deep learning to quantify innervation changes during wound healing in mice, finding a strong correlation between nerve fiber density and re-epithelization.

The paper identifies wound fibroblast phases and matrix patterns that define cancer-associated fibroblast subtypes with prognostic relevance in skin cancer.

The paper identifies 17 microRNAs involved in chronic wound healing through integrative RNA-omics analysis and suggests they as therapeutic targets.

This paper develops a deep learning pipeline for automatic wound detection and size estimation in lab mice images, showing high fidelity results with minimal human intervention.

This paper develops a mathematical model to identify optimal spatio-temporal regimes for wound treatment by analyzing macrophage polarization dynamics.

The paper profiles single-cell RNA sequencing data from diabetic foot ulcers to identify cell types and gene expression patterns associated with wound healing.

The paper uses integrated spatial multi-omics to study fibroblast fate during tissue repair and defines mechanisms controlling cell fate in wound healing.

The paper uses single-cell transcriptomics to identify MHCII-expressing keratinocytes in pressure ulcers linked to poor healing outcomes.

The paper investigates how Foxn1 deficiency impacts hypoxia-regulated factors in skin wound healing, showing scarless healing and altered Hif-1 regulation.

The paper identifies the role of the insulin signaling pathway in regulating actin dynamics during cell wound repair in Drosophila.

This study identifies Lef1-expressing papillary fibroblasts in developing mouse skin that can enhance adult skin regeneration when ectopically expressed, without disrupting normal development.

This study identifies a cell-circuit framework for wound healing and fibrosis, revealing three fibrosis outcomes and parameters that control the transition from healing to fibrosis.

This study shows that autologous micrograft therapy accelerates wound healing by enhancing fibroblast migration through ERK pathway activation and increased matrix metalloproteinase activity.

This study investigates salamander skin regeneration and development, finding that regeneration follows a developmental pathway distinct from direct development, requiring ECM remodeling and fibroblast activity.

The paper shows fibroblast state switching between proliferation and ECM deposition defines dermal architecture and is critical for wound healing.