Bacteriophages and microbial interactions

This study uses high-resolution transcriptomics to reveal complex transcriptional architecture in the archaeal virus SSV1, including new transcription start and termination sites and antisense RNAs.

This study investigates how RNA virus infection reprograms the metabolism of a marine diatom, revealing significant changes in lipid and nitrogen pathways and stress responses.

This study develops a reverse-genetics system for a virophage to investigate gene functions and their role in modulating giant virus replication.

This study shows that a temperate phage can both aid Bifidobacterium gut colonization and increase sensitivity to antibiotics in honey bees.

The paper shows constant warming enhances phage-mediated coexistence of bacterial species, while variable warming disrupts it by reducing phage control.

The paper investigates how virus-grazer interactions affect Prochlorococcus mortality, virus production, and organic matter aggregation in a simplified marine ecosystem.

This study shows that sequential use of two K1-targeting phages can improve efficacy against Klebsiella pneumoniae by exploiting resistance-virulence trade-offs and avoiding shared resistance pathways.

This study identifies Bd0967 as a C-terminal processing protease in Bdellovibrio bacteriovorus that degrades flagellins and regulates developmental progression.

The paper shows how phages evade bacterial immune systems by using allelic variation and an anti-defense hotspot, revealing a similarity to a human protein.

This study shows that prophage induction in Lactiplantibacillus plantarum releases extracellular vesicles that support host growth during nutritional stress.

The paper shows that elevated temperature inhibits viral life cycle stages in Gephyrocapsa huxleyi but allows reversibility under prolonged heatwave conditions.

The paper establishes a tripartite co-culture system to study defensive mutualism between a Nanobdellati symbiont and its host, revealing glycan-mediated protection against viral infection.

The paper compares divergence of terrestrial and marine DNA viromes from reference databases, finding terrestrial viromes more divergent, especially in polar regions.

This study develops a new phage isolation method and evaluates phage efficacy in different biological matrices, finding that phage activity varies significantly and sustained activity depends on maintaining favorable phage-to-bacteria ratios.

LBV-Seq enables de novo reconstruction of DNA and RNA viral genomes from low-input samples, achieving broad genome coverage and resolving strains and gene-level variation.

The paper develops a targeted proteomic assay for quantifying bacteriophages, demonstrating its accuracy and precision compared to plaque assays.

The paper investigates bacteriophages infecting Ralstonia solanacearum in Reunion Island, identifies locally adapted phages, and develops a phage cocktail to control bacterial wilt.

This study profiles the nasopharyngeal phageome of post-weaning piglets using paired DNA-microbiome and virus-like particle-enriched metagenomics, revealing a modular ecological structure shaped by viral replication strategy and host affiliation.

This study identifies RyDEP as an enzyme that degrades 2'cADPR and 3'cADPR immune signals, inactivating bacterial defense and restoring NAD+.

This study identifies 2,355 PLV populations in marine viromes, revealing their seasonal dynamics and functional roles in coastal ecosystems.

This study identifies DNA-damaging bacteriocins from E. coli that induce prophages and promote lysogeny in the gut microbiota.

This paper compares in vitro methods to characterize phage-antibiotic interactions, finding antagonism between a vibriophage and cefotaxime at MIC/2 concentrations.

The paper predicts Klebsiella phage adsorption at the protein level and identifies conserved receptor-binding motifs that drive host specificity.

This study resolves the structure of bacteriophage T4 at different stages, revealing mechanisms of genome delivery and superinfection exclusion.

This study shows that a single amino acid substitution in phage T7's DNA polymerase I significantly affects infection dynamics in the T7-E. coli system.

This study shows that soluble mucin glycans delay Escherichia coli phage T4 infection initiation but enhance virion stability and persistence in the gut.

The paper identifies novel viruses in wastewater treatment plants and shows their central role in microbial community structure and evolution through a multilayered network analysis.

This study identifies structural modularity in Klebsiella pneumoniae phage RBPs, showing how modular exchange drives host-range diversification across multiple scales.

The paper develops a genome-based framework to predict bacteriophage infectivity against diverse Pseudomonas aeruginosa strains using machine learning and experimental data.

The paper identifies phages infecting E. coli HS, shows their resistance to restriction via modifications, and links phage infection to a Klebsiella-like capsule.