Amoebic Infections and Treatments

Structural basis for carbohydrate recognition by the Gal/GalNAc lectin of Entamoeba histolytica

This study determines the structure of the Entamoeba histolytica Gal/GalNAc lectin, revealing its carbohydrate binding mechanism and antibody epitope, which informs vaccine development.

Enteropathogenic Escherichia coli induces Entamoeba histolytica Levy-like movement on fibronectin-rich substrate by reducing traction forces

This study shows that enteropathogenic Escherichia coli enhances Entamoeba histolytica motility on fibronectin-rich substrates by reducing traction forces and altering F-actin distribution.

Entamoeba histolytica extracellular vesicles drive pro-inflammatory monocyte signaling

This study shows that extracellular vesicles from Entamoeba histolytica drive pro-inflammatory monocyte signaling, contributing to male-biased immunopathology in amebic liver abscesses.

EhRacM differentially regulates macropinocytosis and motility in the enteric protozoan parasite Entamoeba histolytica

This study identifies EhRacM's role in regulating macropinocytosis and cell migration in Entamoeba histolytica through gene silencing and functional analysis.

Genome-Wide Association Study Reveals Genetic Link Between Diarrhea-Associated Entamoeba histolytica Infection And Inflammatory Bowel Disease

This study identifies genetic variants associated with Entamoeba histolytica infection and links them to inflammatory bowel disease susceptibility.