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timePlex increases LC-MS throughput by multiplexing samples in the time domain, achieving combinatorial scaling and enabling high-throughput proteomics.

This study examines how brachial plexus birth injury affects trabecular bone microstructure and morphology in different locations, showing location-dependent detriments and differential effects based on injury type and limb disuse.

This study shows high glucose and fluid shear stress together enhance metastatic breast cancer cell migration, mediated by focal adhesion kinase.

PSMtags enhance peptide detection and sequence identification in proteomics, enabling 9-plexDIA and significantly increasing sample throughput.

This paper introduces CereBRLSIM, a digital twin that predicts cerebral blood flow and CVR mechanisms in neurocritical care patients with higher accuracy than machine learning models.

This paper develops a calibration-free P300 BCI system with real-time performance comparable to offline benchmarks, using pre-trained models and a small electrode setup.

This paper develops an efficient one-step enzymatic method to synthesize cyclic-2,3-diphosphoglycerate using MfcDPGS from Methanothermus fervidus, achieving high conversion efficiency and scalability.

The paper validates ephaptic coupling in human neuronal circuits using a reproducible in vitro method, showing reduced action potential velocity and increased synchronization.

This study shows common AAV vectors transduce multiple human brain cell types in organotypic slices, with astrocytes showing the most protein expression, and introduces a pipeline for optimizing AAV vectors.

This paper presents a multi-scale systems approach to design biomanufacturing systems for CO2 fixation, showing the reductive glycine pathway can fix CO2 at higher rates than photosynthetic organisms.

This study uses magnetic sorting to enrich human stem cell-derived islets for CD49a, improving β-cell identity and function for diabetes therapy.

This paper introduces a self-supervised learning method for cell segmentation that outperforms Cellpose in accuracy and reduces reliance on labeled data and computational expertise.

This paper introduces two novel methods to incorporate DBCO into S. aureus peptidoglycan for SPAAC-mediated cargo labeling, showing improved stability and reduced toxicity compared to existing approaches.

This paper compares a digital microfluidic electroporation system (triDrop) with commercial systems for engineering human T cells, showing improved viability, efficiency, and reduced dysregulation of pathways.

This paper shows that alternating 2D and 3D culture reduces cell size and extends the lifespan of placenta-derived MSCs while preserving their immunomodulatory function.

The paper develops a high-throughput method to measure single-cell density and applies it to study immune cell states and drug response in patient samples.

This paper develops a method to create controlled vascular networks using magnetic assembly of endothelial-cell seeds, enabling precise interconnectivity and applications in drug testing and tissue engineering.

This paper demonstrates transient prime editor expression in mice to correct a genetic liver disease, reducing blood phenylalanine levels below the therapeutic threshold.

This paper develops engineered ECM fibers using Anchored Cell Sheet Engineering to treat volumetric muscle loss in rats, showing improved tissue regeneration and preservation compared to commercial ECM.

This study benchmarks four cervical spinal cord RF coils at 7 T MRI across multiple centers, identifying performance differences and proposing a standardized evaluation protocol.