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The paper investigates how multi-trait selection affects genetic correlations in populations, using theory and a case study on dairy cattle data.

The paper maps eQTLs in yeast using single-cell RNA sequencing, revealing tradeoffs between growth and reproduction through allele-specific effects on gene expression and cell-cycle progression.

This study shows that small chemical molecules can repair osteoarthritis in rats by epigenetic reprogramming, improving cartilage structure and function.

The paper shows that proteostasis influences gene dosage evolution in antibiotic-resistant bacteria by modulating DHFR expression and copy number changes under trimethoprim pressure.

The paper shows that EBAX-1/ZSWIM8 destabilizes miRNAs, leading to transgenerational memory of a predatory trait in nematodes.

The paper identifies a SNP variant associated with resistance to viral nervous necrosis in European sea bass by integrating genetic and functional genomic data.

The paper analyzes 11,125 trio exomes to explore the relationship between genetic variants and phenotypic features in neurodevelopmental disorders, finding significant clinical similarities and phenotypic gradients.

This study identifies PQM-1 as a stress-responsive transcription factor that promotes proteostasis and organismal survival through a secondary wave stress response mechanism.

The paper identifies functional enhancer variants at QT interval GWAS loci using MPRA and predicts their impact on cardiac gene expression.

The paper shows that non-autonomous P-element insertions can stabilize TE copy numbers without piRNA defence, revealing a novel mechanism for TE population dynamics.

The paper uses single-nucleus RNA-sequencing to link molecular variation in hypothalamic neurons to social motivation behavior in mice, identifying actionable targets for social deficit disorders.

This study examines how genetic factors and sex influence oxycodone self-administration in rats, finding sex differences in intake and heritability in specific strains.

The paper introduces a haplotype-based method to estimate maternal and fetal genetic contributions to pregnancy outcomes, finding that gestational duration is mainly influenced by maternal haplotypes while fetal size is influenced by both maternal and paternal haplotypes.

The paper sequenced transcriptomes of six sea anemone species to identify toxin gene complements and analyze their evolutionary distribution across 26 species.

The paper shows that altered H3K27me3 landscapes can be inherited across generations in C. elegans, regulated by chromodomain proteins with opposing roles.

The paper identifies regulatory elements controlling Ets1 expression in B cells but not T cells, using epigenetic and reporter assays in mice.

This paper presents a SNP-based crossover map for Drosophila mauritiana, showing reduced centromere suppression of crossing over compared to D. melanogaster.

The paper compares methylation profiles of placentas with non-malarial and PM-associated FGR, finding distinct differentially methylated CpGs and a shared hypomethylated site in BMP4.

This paper introduces RAEFISH, a spatial transcriptomics technology that achieves whole-genome coverage and single-molecule resolution in intact tissues, enabling comprehensive analysis of RNA localization and cell interactions.