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ntRoot infers human super-population ancestry from genomic data with high accuracy and efficiency, outperforming traditional methods on large datasets.

This paper enhances GPT models for genomics by integrating variant annotations via RAG and fine-tuning, improving variant interpretation accuracy and efficiency.

RegionScan provides an R package for region-level genome-wide association testing and visualization, supporting multiple-variant and single-variant hypothesis testing with LD-adaptive region definition.

The paper investigates the selectivity of the iMab antibody for i-motif structures, showing it binds both intramolecular and intermolecular iMs, and highlights the impact of experimental conditions on binding.

The paper uses hierarchical clustering to analyze over 3,000 epigenomes and characterize relationships among epigenetic modifiers, their modifiers, and immune cell types.

Learning and removing Tn5/DNase-I sequence bias lets a small base-resolution CNN (ChromBPNet) recover TF motifs and footprints from accessibility data and rival Enformer at predicting chromatin QTL effects.

The paper develops a novel method to estimate soft tissue weight in bivalves using shell surface area, outperforming traditional models in accuracy and bias reduction.

This study identifies a synthetic peptide, PAN4, with antimicrobial, stress-tolerant, and anti-tumor properties in Drosophila, showing potential for improving honeybee health and resilience.

This study identifies a structural variation in the CDKN2A gene that regulates shank color in chickens by inhibiting dermal melanin production.

The paper evaluates the usefulness criterion for mate selection in breeding programs and finds it provides little benefit over selecting parents based on predicted family means.

The paper introduces sciMETv3, a high-throughput single-cell DNA methylation profiling method, achieving 100-fold higher cell throughput and compatibility with multimodal assays.

This paper reviews advances in the ReMOT technique for genetic modification in insects, highlighting its versatility, efficiency, and potential for optimization.

This study investigates how mutations in the CRX gene affect cooperative dimerization, leading to developmental defects in photoreceptors and retinal disease.

The paper develops a split-CRISPR/Cas9 system for sex conversion in Mediterranean fruit flies to improve population control strategies.

This study identifies DNA repair pathways that prevent acetaldehyde-induced mutagenesis in yeast and corroborates findings in human liver cancers.

The paper introduces EasyGuide CRISPR, a CRISPR toolkit for engineering E. coli strains to grow on sucrose, and demonstrates its application in adaptive evolution experiments.

The paper shows ZNF143/ZFP143 is an essential transcription factor with no general looping function, functioning independently of CTCF and regulating mitochondrial and ribosomal genes.

This study identifies a mutation in the LRP2 gene responsible for celestial-eye in goldfish and shows parallel evolution of this gene in different eye phenotypes under artificial selection.

This study examines how different domains of spatial ability predict STEM educational outcomes and finds that object manipulation tests are most predictive, with genetic factors explaining most of the associations.

This study shows that sex and genetic background affect oxycodone self-administration in rats, with heritability estimates ranging from 0.25 to 0.54.