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The paper directly identifies de novo mobile element insertions in human sperm using long-read sequencing and finds age-related increases in retrotransposition rates.

The paper evaluates genomic prediction models for agronomic traits in perennial ryegrass under genotype x environment interactions, showing improved accuracy when accounting for these interactions.

This study examines how mating status influences exercise response and fitness tradeoffs in female Drosophila, finding that mating affects climbing performance, lifespan, and fertility.

This paper describes a novel meiotic mutant in maize that produces unreduced female gametes, enabling clonal seed production when combined with another mutant, advancing synthetic apomixis research.

The paper introduces PCAN, a resource integrating high-throughput phenotyping of mouse models for Prader-Willi syndrome to evaluate phenotypes and therapeutic strategies.

This study shows that p97 and PML nuclear bodies regulate cGAS degradation after DNA damage, affecting the DNA damage response and senescence.

The paper shows that CLN3 can function independently of WHI5 in regulating cell size for Start in yeast, as the double mutant exhibits near-wild-type cell size.

This study shows that in C. elegans male spermatogenesis, crossover-promoting factors can recruit to chromosomes without SPO-11 activity, indicating weakened crossover control compared to hermaphrodite oogenesis.

This study examines how genotype and sex influence paraquat-induced oxidative stress effects on functional aging and lifespan in Drosophila melanogaster.

The paper identifies ZNF-236 as a key factor maintaining quiescence of stress-induced genes in C. elegans, showing that this silencing is an active genomic state, not passive.

The paper combines SNP haplotyping and intensity analysis to identify meiotic and mitotic aneuploidies in preimplantation embryos, finding 37% aneuploidy rate with equal meiotic and mitotic cases.

The paper develops a machine-learning classifier to automate detection of ataxia and convulsions in Drosophila Shu mutants, showing reliable classification of walking and immobilization with moderate sensitivity for uncoordinated movement.

QWENDY infers gene regulatory networks from single-cell gene expression data across four time points, outperforming existing methods on experimental data but not synthetic data.

This study shows that telomere length is maintained in telomerase-deficient zebrafish during caudal fin regeneration via the ALT pathway, suggesting its role in supporting high cell proliferation rates.

The paper compares the effects of three different germline mutations on longevity and fat metabolism in C. elegans, finding distinct physiological outcomes.

This study benchmarks five loss-of-function perturbation tools for studying noncoding genome function, finding dual-SpCas9 is most effective for targeting CREs and recommending RNA interference for noncoding RNA genes.

This study shows that separase interacts with nuclear lamins in Drosophila and humans, affecting nuclear organization and lamin levels, indicating an evolutionarily conserved role.

This study identifies HEIP1 as a master regulator of crossover formation in mouse meiosis by orchestrating the recruitment of pro-crossover proteins.

This paper presents an analytical solution for estimating SNP-heritability in biobank-scale and distributed datasets, achieving high precision and efficiency.

The paper develops optimized core collections for genetic studies using a worldwide flax germplasm, balancing genetic diversity and representativeness for improved QTL detection in GWAS.