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The paper resolves centromere structure in Drosophila, showing conserved architectural domains despite DNA sequence variation.

The paper identifies the E2F1 regulon as a driver of sex-specific vascular programming in fetal endothelial progenitors exposed to GDM, revealing a proliferative emergency in females.

This study uses bulk RNA sequencing in a porcine model of neurocysticercosis to identify transcriptional signatures associated with viable parasite persistence and post-treatment lesion disruption.

This study analyzes codon usage bias across 262 plant species, finding lineage-specific patterns driven by mutation, selection, and translational optimization.

The paper measures nucleosome occupancy in mouse and human sperm using single-molecule footprinting and finds species-specific differences in residual nucleosome retention.

The paper identifies RNA viruses and transposable elements in Drosophila using single-nucleus transcriptomics, revealing tissue-specific viral tropism and TE expression patterns.

This paper introduces DORAS, a PCR-free method for targeted genomic sequencing that improves MLST typing efficiency compared to whole-genome sequencing.

The paper describes the gene model for the tgo ortholog in Drosophila busckii as part of a dataset studying IIS pathway evolution.

The paper presents a chromosome-scale genome assembly of Halocafeteria seosinensis using long-read sequencing, enabling detailed genomic analysis of a halophilic protist.

The paper updates a yeast reference transcriptome using direct RNA sequencing to improve UTR annotation and provides a reusable pipeline for future updates.

The paper introduces gmMAP, a framework that integrates metabolite GWAS with single-cell and spatial transcriptomes to map metabolic programs at cellular and spatial resolution, revealing associations between exogenous metabolites and cellular states.

This study uses spike-in normalization to analyze age-related changes in gene expression across mouse cell types, finding decreased mRNA content in non-immune cells and increased in immune cells, along with reduced gene expression and shared regulatory processes between ageing and proliferation arrest.

The paper identifies diverse mobile genetic elements in Xanthomonas species and their role in adaptive traits through comparative genomic analysis.

The paper introduces and benchmarks two droplet-based single-nucleus assays for chromatin accessibility and gene expression, showing they are cost-effective and produce high-quality data.

This study characterizes endogenous retroviruses in the slow loris, identifying active retroviral elements and their evolutionary dynamics across strepsirrhine primates.

The paper maps H3K4me3 in T. cruzi and finds it correlates with transcriptional activity and genomic span of initiation regions.

The paper presents a high-quality reference genome for Hymenolepis diminuta using PacBio HiFi long-read sequencing, achieving high contiguity and completeness.

This study analyzes interspecies variation in the 45S rDNA locus across vertebrates, revealing lineage-specific differences in organization, copy number, and sequence evolution.

The paper presents a draft genome assembly of the slipper lobster and identifies an XX/XY sex-determination system, along with a diagnostic PCR marker for monosex aquaculture.

HiFiRe3 improves rare structural variant detection by reducing artifacts through error suppression and correction strategies across long and short-read sequencing platforms.