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This study investigates the role of H2A.Z isoforms in intestinal homeostasis, showing they regulate stemness, lineage differentiation, and enterocyte differentiation with opposing effects.

This study shows that 2-monopalmitin, but not 1-monopalmitin or palmitic acid, improves hypothalamic leptin responsiveness and metabolic outcomes under overnutrition.

This study evaluates the impact of Virtual Online Physical Education on university students' physical fitness, finding gender-specific effects on BMI, lung capacity, and aerobic capacity.

The paper identifies squalene and fatty acids as potential pheromone components in human sweat through GC-MS analysis and speculates on their role in transmitting olfactory information.

This study compares radiography and computed tomography for assessing condylar stress fracture risk in Thoroughbred racehorses, finding that CT provides better sensitivity and reliability for risk assessment.

This study shows that Hpa2 regulates endothelial permeability and prevents proteinuria by modulating VEGFA and FGF signaling through HS shedding.

This study evaluates the activity of digestive enzymes in Octopus maya, finding that acidic proteases are more active at higher temperatures than alkaline proteases, with lower activation energy for alkaline enzymes.

This study investigates how THRB affects diurnal hepatic lipid metabolism in adult male mice, finding THRB deficiency disrupts metabolic rhythms and promotes steatosis.

This study identifies key factors affecting cerebral blood flow measurement accuracy using phase contrast MRI and provides guidelines for optimal settings.

The paper identifies INS-7, an ancestral insulin superfamily peptide in C. elegans, as a gut-to-brain signal that counteracts neuronally driven fat loss during fasting.

This study investigates the role of the mitochondrial pyruvate carrier (MPC) in adipose glucose partitioning, finding sex-dependent effects on triglyceride synthesis and metabolic adaptation in mice.

The paper identifies functionally conserved lncRNA metabolic regulators in human and mouse livers that regulate triglyceride levels through a shared mechanism involving PABPC1 binding.

This study identifies an upstream alternative polyadenylation event in SCN5A that generates a short transcript encoding a mitochondria-localized NaV1.5 N-terminal fragment, which affects cardiomyocyte respiration.

This study shows that HDI sodium butyrate improves β cell function and calcium signaling in diabetes by restoring STIM1 and SOCE, and inhibiting GSK-3 through AKT.

This study shows that cholesterol depletion alters Nav1.7 structure and function, affecting its gating and drug response, with implications for pain management.

This study identifies liver-enriched DPP4 as a driver of gut inflammation in diabetes by inhibiting autophagy, leading to increased immune cell infiltration and colitis.

This study shows that mucociliary clearance is impaired in small airways of cystic fibrosis pigs, with impaired clearance exacerbated by purinergic agonist stimulation.

This study shows that cardiac dysfunction in septic shock occurs without high catecholamine levels or microvascular ischemia, and epinephrine infusions cause prolonged microvascular perfusion issues.