Discover, rate, and discuss biology preprints.

The study shows that warm blood meals in tsetse flies shorten pregnancy duration and increase milk protein production, enhancing reproductive output.

This study uses 2D speckle tracking echocardiography to assess diastolic dysfunction in T2D mice, finding impaired strain rates and regional susceptibility in the anterior left ventricular wall.

The paper examines how tiger competition affects leopard diet and physiology in Rajaji Tiger Reserve, finding that sympatry with tigers increases nutritional stress in leopards.

This study shows SARAF deficiency causes age-dependent obesity, reduced metabolic rate, and behavioral changes, with protective effects when SARAF is removed from the hypothalamus.

This study investigates wheat's response to waterlogging using metabolomics and transcriptomics, identifying alanine as a key metabolite for balancing carbon/nitrogen between roots and shoots.

This study finds that water salinity does not affect acute thermal tolerance in zebrafish after short or long exposure, but notes unexpected behavior in high salinity conditions.

This study evaluates autonomic nervous system modulation in unanesthetized adult medaka using heart rate variability, showing frequency-dependent parasympathetic and sympathetic influences.

This study shows that antagonist tendon vibration reduces estimates of persistent inward currents in human motor units during isometric contractions.

This study identifies TMEM65's role in mitochondrial calcium regulation, showing its loss causes mitochondrial disease and suggesting therapeutic targeting of mitochondrial calcium as a potential treatment.

This study shows that reducing SURF4 in the liver decreases PCSK9 and increases LDLR, leading to lower plasma cholesterol despite reduced lipoprotein secretion.

The paper argues for more comprehensive experiments on phytoplankton responses to climate change by using multiple levels of temperature and CO2 to better predict future population dynamics.

This study shows metformin increases GDF15 but does not rely on the GDF15-GFRAL pathway for its weight-lowering effects in mice.

This study shows that obesity leads to irreversible mitochondrial dysfunction in visceral adipose tissue, which persists despite lifestyle interventions.

The paper shows phosphatidylserine (PS) localizes to myoendothelial junctions (MEJs) in endothelium, inhibiting PIP2-mediated Kir2.1 activation to regulate vascular diameter.

This study shows that reduced lipid content in alveolar macrophages correlates with clinical improvement in patients with Pulmonary Alveolar Proteinosis.

This study identifies PRRs regulating inflammatory osteoclasts and shows that S. boulardii reduces bone loss by targeting these cells.

This study shows that a gain-of-function Trpc6 mutation in mice causes minimal susceptibility to renal injury in various models.

This study shows that IGF-1 therapy increases muscle size and strength in a rodent PAD model, with greater effects in female mice.

This study investigates the role of FGF21 in calorie-restricted diet-induced metabolic changes in mice, finding it dispensable for most effects but sex-specific in adipose tissue beiging.

This study shows aging reduces nerve density in the left ventricle and dysregulates neuro-regulatory genes, leading to reduced heart rate variability.