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This study examines sex differences in cardiopulmonary and neuromuscular responses to high-intensity interval exercise, finding greater hyperpnoea in females during early intervals and lesser decreases in contractile function post-exercise.

The paper examines how genomic composition in polyploid salamanders predicts physiological responses to temperature, finding a trade-off between water loss resistance and metabolic rate in hybrids.

The paper shows dietary lipid is deposited in skin, altering its thermal properties and energy regulation within days.

This study shows that LPS differentially affects phagocytosis in M1- and M2-like macrophages via PGE2 and EP4 signaling, with NSAID inhibition increasing phagocytosis in M1-like macrophages.

This study shows Lactobacillus modulates the gut microbiome to reduce inflammation and improve RV function in PAH by counteracting GP130-mediated microtubule remodeling.

This study identifies TRPV4-expressing macrophages as regulators of lymphatic vessel function through TXA2 receptors, suggesting therapeutic targets for lymphedema.

This study identifies the C-terminal domain as the temperature sensor in TREK channels and shows that microtubule interaction and PKA phosphorylation regulate their thermosensitivity.

This study constructs dose-response curves for lower body negative pressure (LBNP) to quantify cardiovascular effects across different postures and identifies its potential to reduce jugular venous flow stagnation during spaceflight.

This study examines how apocarotenoids like ionones and abscisic acid affect growth, sporulation, toxin production, and gene activity in two Fusarium oxysporum strains, revealing strain-specific responses.

This study shows metformin protects the heart from chronic intermittent hypoxia by activating AMPK2, which phosphorylates and inhibits HIF-1α, reducing mitochondrial damage.

This study shows that Tldc2 knockout in B-type kidney intercalated cells impairs urine alkalinization and bicarbonate secretion, suggesting Tldc2's role in renal acid-base regulation.

This study evaluates the impact of heat stress on rapeseed grain yield during two phases of grain filling in southern Chile, finding that Lumen is more heat-tolerant than Solar CL.

This study tests if thermoneutral housing prevents social isolation-induced bone loss in male mice but finds no such effect, suggesting cold stress is not the primary mechanism.

This study examines how age and sex hormones affect female neuromuscular function across adulthood, finding accelerated decline around menopause linked to hormonal changes and muscle vulnerability.

This study shows that HDAC3's cardioprotective role in adult hearts is independent of its enzymatic activity, as enzyme-inactive HDAC3 can rescue gene expression and cardiac function.

This study evaluates the metabolic demand of e-bike riding at different intensities and finds that e-bike assistance reduces metabolic demand below the threshold for cardiorespiratory benefits.

This study examines genotype-dependent responses to water deficit in maize, finding increased cell wall digestibility linked to reduced p-coumaric acid and lignification in the rind.

This study develops a computational model of calcium homeostatic feedback to simulate atrial fibrillation progression from healthy to remodeled tissue.

This study examines how aging, endurance training, and denervation affect immune signaling and mitochondrial function in skeletal muscle, finding that training reduces age-related inflammation and mitochondrial dysfunction.