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This study shows that vertical sleeve gastrectomy in mice reduces plasma cholesterol without weight loss by enhancing bile acid synthesis and hepatobiliary elimination.

This study examines how high-altitude exposure affects mitochondrial subcellular distribution, ultrastructure, and respiratory capacity in sea-level residents.

This study investigates whether blood flow occlusion during low-intensity exercise induces hypoalgesia, finding no change in pain pressure thresholds despite increased perceived pain and effort.

This paper describes a novel extracorporeal placental support model in sheep, demonstrating fetal survival for over 16 hours after hysterectomy.

This study shows ZIP14 facilitates manganese efflux from the brain by relocalizing to the basolateral membrane in BBB endothelial cells, and its deletion causes Mn accumulation.

The paper develops queue models to assess left ventricular blood transit and shows that flow transport, not ejection fraction, determines stasis in patients with impaired systolic function.

This study investigates how aphantasia affects emotional engagement with stories, finding reduced emotional but not cognitive engagement in aphantasics compared to controls.

This study identifies RCOR1 as a positive regulator of myogenesis and skeletal muscle regeneration by interacting with LSD1 and MyoD.

This study identifies a human GR variant, rs6190, that increases cholesterol and atherosclerosis risk by enhancing GR activity in mice and human cells.

This study investigates the role of BAT ADH5 in aging, showing that its loss accelerates BAT senescence and metabolic decline, while HSF1 activation mitigates these effects.

This study assesses the reliability of tactile perception and suppression across time, finding robustness in resting conditions but variability in movement conditions without clear patterns.

This study shows that nutrient excess remodels pancreatic islet innervation through Schwann cells, impairing glycemic control, and demonstrates that neuromodulation can improve outcomes.

This study shows that normothermic kidney preservation with red blood cells causes iron accumulation and ferroptosis, leading to kidney injury, and suggests alternatives to mitigate these effects.

This study shows that the proton-activated chloride channel inhibits SARS-CoV-2 entry by blocking endosomal acidification and the cathepsin-dependent pathway.

This study compares the physiological mechanisms of action cancellation and cancellation of action cancellation using EMG, finding no difference in cancellation speed between conditions.

This study identifies the insulin/insulin-like growth factor signaling pathway as a key determinant of higher fat storage in Drosophila females through increased dietary sugar intake and Dilp3 expression.

This study investigates whether oral contraceptive use affects grip strength and neuromuscular activation in females during wrist/hand immobilization and rehabilitation, finding no significant differences between OC users, non-users, and males.

This study investigates the distribution and function of atrial granules in guinea pig and goat cardiomyocytes, finding they are acidic calcium stores closely associated with the sarcoplasmic reticulum and increase in number during atrial fibrillation.

This study investigates sex differences in bone loss associated with MASLD using DIAMOND mice, identifying potential liver-secreted factors involved in bone resorption.

The paper introduces the corrected oxygenation gradient (COG) as a new metric that integrates gas exchange, oxygen extraction, and ventilatory adequacy to improve diagnostic precision in respiratory and circulatory conditions.