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Genetic Variation in Photosynthetic Maintenance and Post-Chill Recovery for Early Season Maize Plantings

This study evaluates genetic variation in maize's response to chilling stress and recovery, identifying heritable traits linked to cold resilience.

Hidden infections: Linking parasite ecology, fish health and stakeholder perceptions in Nile tilapia aquaculture in central Kenya

The paper investigates parasite infections in Nile tilapia aquaculture, finding that monopisthocotylan parasites are prevalent and linked to gill lesions, while stakeholders rarely identify parasites as a health cause.

European LD proxies lose tagging for 43% of GWAS leads in the African panel: a chromosome 22 analysis with SwiftLD, an 826-fold faster, byte-identical vcftools LD

SwiftLD, a faster alternative to vcftools for computing LD, shows European LD proxies poorly tag 43% of GWAS leads in African populations.

Sex differences in cell type-specific transcriptional programs and GPCR signaling in the human subgenual anterior cingulate cortex

The paper identifies sex-specific transcriptional differences in specific cell types of the human subgenual anterior cingulate cortex and links them to GPCR signaling differences in mice.

Diversification of budding yeast polarization dynamics after compensatory experimental evolution

This study shows that evolution can restore cellular function without conserving microscopic organization, leading to novel molecular phenotypes in budding yeast.

Human-caused ignitions and plant invasion drive fire-regime change in a dryland biodiversity hotspot

The paper quantifies how human ignitions and herbaceous fuels drive fire regime changes in the Sonoran Desert, showing human-caused fires dominate and spread more with increased vegetation cover.

Social vision expands into auditory cortices of people born deaf: evidence from naturalistic film and encoding models

The paper compares neural processing in deaf and hearing adults during a film task, finding enhanced visual encoding in auditory cortices of the deaf.

Temporal Variability in Brain Connectivity for Estimating Two-Year Clinical Severity in Mild Cognitive Impairment

The paper examines if temporal variability in brain connectivity improves prediction of two-year clinical severity in mild cognitive impairment compared to static connectivity measures.

Growth-driven mechanical buckling as a mechanism of age-related tortuosity in human cerebral arteries

This study models age-related tortuosity in human cerebral arteries as growth-driven mechanical buckling under spatial constraints, supported by imaging data from MRI.

A Binuclear Cluster Supports Functional Asymmetry in Dark-Operative Protochlorophyllide Reductase

This paper identifies a binuclear [Cu2S2] cluster in DPOR that mediates functional asymmetry between its active sites.

Increased activity without changes in coupling between somata and apical dendrites during visual mismatches

This study examines neural responses in mouse visual cortex to natural and artificial visual stimuli, finding increased activity in response to natural mismatches but no change in dendritic-somatic coupling.

Translating chemical reactions into enzyme sequences enables formate dehydrogenase engineering

This paper introduces REXzyme, a model translating chemical reactions into enzyme sequences, and demonstrates its ability to generate active formate dehydrogenases for CO2 reduction.

An open-access neuroimaging-compatible virtual town task for assessing human spatial navigation

The paper introduces an open-access virtual navigation task compatible with neuroimaging, demonstrating its use with EEG and behavioral tracking in human participants.

A protein language model for domain, functional site, and variant effect prediction

PALM, a protein language model, predicts domain, functional site, and variant effects with high accuracy using curated sequence data and outperforms existing models in multiple benchmarks.

Structural basis for inefficient G protein coupling by Frizzled receptors

The paper identifies detergent LMNG as stabilizing a weak FZD-G protein interface, revealing that FZDs inherently weakly couple to G proteins and preferentially signal through DVL.

Dendrite Control Theory: A Unifying Framework Bridging Neuronal Morphology And Dendritic Voltage Behavior

This paper applies control theory to dendritic structures, showing how morphology and input organization affect resilience and energy cost, with implications for neuronal function.

Genome evolution and glycosyltransferase diversification shape asperosaponin biosynthesis in Dipsacus asperoides

The paper reconstructs the asperosaponin biosynthesis pathway in Dipsacus asperoides by integrating genomics, transcriptomics, and biochemical analyses, revealing gene family diversification and glycosylation order.

Epigenetic reprogramming by promoter hypomethylation is linked to aberrant gene expression and transcriptomic plasticity in colorectal cancer

The paper identifies promoter hypomethylation as a driver of transcriptomic plasticity and aberrant gene expression in colorectal cancer, linking it to distinct cell states and metastatic behavior.

Dated public evidence and known genes for retrospective evaluation of gene prioritization

The paper provides per-gene evidence tables from public resources for retrospective gene prioritization, including dates and leakage risk grades for four disease areas.

SPECHTacle: An Efficient Detection and Visualization of Cell Specific Regulation in Single Cell-Based Experiments Using a Novel Combinatorial Computational Tool

SPECHTacle efficiently identifies and visualizes cell-specific regulatory changes in single-cell experiments using optimal transport and entropy analysis.