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The paper shows top-down semantic predictions align phonetic neuronal dynamics in the human superior temporal gyrus during speech processing.

This study uses smFRET to reveal conformational changes in the prokaryotic NavAb channel during slow inactivation, identifying key residues that coordinate structural transitions.

This study introduces OpenCGChromatin, a model that simulates chromatin structure and phase separation, revealing how linker-DNA length and histone modifications affect chromatin organization.

This study identifies structural variants in male infertility using optical genome mapping, finding rare variants in 25% of patients that may contribute to infertility.

This study shows that fresh frozen plasma reduces lung injury in mice with abdominal sepsis and hemorrhagic shock by preventing neutrophil degranulation and syndecan-1 shedding.

This study uses AlphaFold2 to analyze the structural diversity of effector proteins in rust fungi secretomes, identifying structurally related clusters and metal-binding effector candidates.

This paper evaluates long-read sequencing with targeted assembly for accurately analyzing the opsin gene cluster, showing high concordance and improved detection of color vision deficiencies and carrier status.

Two Portuguese rice-blast fungus isolates were assembled from PacBio HiFi reads into near-complete genomes; one isolate lacks Avr-Pii, Avr-Pia and Avr-Pik yet remains virulent on two rice cultivars.

The paper investigates the genetic and metabolic basis of the trade-off between carotenoids and dry matter in cassava roots, finding no direct transcriptional co-regulation but suggesting regulatory and metabolic links.

This study investigates the role of Cwc15p in S. cerevisiae splicing, finding it stabilizes and facilitates structural transitions of the spliceosome active site, important for splicing under nonoptimal conditions.

This study shows that transcranial magnetic stimulation (TMS) effects on cognitive control depend on the cognitive state during stimulation, enhancing outcomes when aligned with active cognitive tasks.

This study shows wild-type and mutated beta-catenin differently repress RND3/RHOE expression in hepatocellular carcinoma through distinct mechanisms.

This study investigates genetic and sex-specific factors influencing bone response to PTH in mice, finding strong heritability and sex-dependent mechanisms.

The paper analyzes a mathematical model of oncolytic virus-immune interactions to explain why oncolytic viruses rarely achieve complete tumor regression, identifying stacked traveling wave solutions.

The paper curates a genome-scale nucleotide diversity panel of non-human primates using ploidy-aware variant calling and multiple-genome alignment.

This study identifies a small molecule, SCC944, that targets ARF1-CSW interactions and reduces GTP-bound ARF1, showing potential as a therapeutic for ALS/FTD.

This study examines how tenuazonic acid affects immune and intestinal epithelial cells, showing opposing immunomodulatory effects depending on cell type.

This study shows that ethanol disrupts long-term potentiation at hippocampus-medium spiny neuron synapses in the nucleus accumbens, with effects persisting during early abstinence.

The paper examines genomic and transcriptomic variation in yeast to determine if cis-regulatory interactions influence aging, finding limited evidence for such interactions.

This paper introduces ACeT, a machine learning framework that predicts formulation and pharmacokinetic risks of monoclonal antibodies using early assay panels, achieving high predictive accuracy and interpretability.