Author

S. Sonam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Approach:statistical model· 1

Frequent Co-Authors

B. Ladoux· 3 shared L. Balasubramaniam· 2 shared R.-M. Mege· 2 shared Y. Toyama· 2 shared A. Bigot· 1 shared A. Doostmohammadi· 1 shared A. Muchir· 1 shared A. S. Yap· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

B. Ladoux

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanical stress driven by rigidity sensing governs epithelial stability

S. Sonam, L. Balasubramaniam, S.-Z. Lin, I. Yow, I. P. Jauma, C. Jebane, M. Karnat, Y. Toyama, P. Marcq, J. Prost, R.-M. Mege, J.-F. Rupprecht, B. Ladoux

The paper shows that substrate stiffness drives mechanical switches in epithelial monolayers, leading to stochastic failure through topological defects.

bioRxiv · Mar 10, 2022Biophysics

Bioengineering a Miniaturized In Vitro 3D Myotube Contraction Monitoring Chip For Modelization of Muscular Dystrophies

N. Rose, S. Sonam, T. Nguyen, G. Grenci, A. Bigot, A. Muchir, B. Ladoux, F. Le Grand, L. Trichet

This paper develops a miniaturized 3D myotube contraction monitoring chip to model muscular dystrophies, showing contractile dysfunction in L-CMD mutant myotubes with reduced starting material requirements.

bioRxiv · Jun 15, 2021 · PreprintBioengineering

Nature of active forces in tissues: how contractile cells can form extensile monolayers

L. Balasubramaniam, A. Doostmohammadi, T. B. Saw, G. Sankara, R. Mueller, T. Dang, M. Thomas, S. Gupta, S. Sonam, A. S. Yap, Y. Toyama, R.-M. Mege, J. Yeomans, B. Ladoux

The paper investigates how epithelial cell monolayers switch from extensile to contractile behavior as intercellular contacts weaken, revealing mechanotransductive responses and implications for cell sorting and tissue dynamics.

bioRxiv · Oct 28, 2020Biophysics