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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
S. Shaw, I. S. Cohn, R. de Paula Baptista, G. Xia, B. Melillo, F. Agyabeng-Dadzie, J. C. Kissinger, B. Striepen
This paper demonstrates genetic crosses within and between Cryptosporidium species, showing genomic recombination and its implications for parasite adaptation and host specificity.
Proceedings of the National Academy of Sciences · Dec 26, 2023Peer-reviewedMicrobiology
R. D. Pardy, K. A. Walzer, B. A. Wallbank, J. H. Byerly, K. M. O'Dea, I. S. Cohn, B. E. Haskins, J. L. Roncaioli, E. J. Smith, G. Y. Buenconsejo, B. Striepen, C. A. Hunter
This study uses single-cell RNA sequencing to analyze how intestinal epithelial cells respond to Cryptosporidium infection and IFN-gamma, showing delayed parasite reduction with cytokine treatment.
bioRxiv · Nov 14, 2023 · PreprintImmunology
I. S. Cohn, B. A. Wallbank, B. E. Haskins, K. M. O'Dea, R. D. Pardy, S. Shaw, M. I. Merolle, J. Gullicksrud, D. A. Christian, B. Striepen, C. A. Hunter
The paper investigates the role of intestinal cDC1s in CD4+ T cell-mediated resistance to Cryptosporidium, showing they support T cell expansion and effector function through IL-12-dependent and -independent mechanisms.
bioRxiv · Nov 11, 2023 · PreprintImmunology
B. E. Haskins, J. A. Gullicksrud, B. A. Wallbank, J. E. Dumaine, A. Guerin, I. S. Cohn, K. M. O'Dea, R. D. Pardy, M. I. Merolle, L. A. Shallberg, E. N. Hunter, J. H. Byerly, E. J. Smith, G. Y. Buenconsejo, B. I. McLeod, , C. A. Hunter
The paper shows that dendritic cells are essential for CD8+ T cell responses to Cryptosporidium effectors, which are secreted by the parasite.
bioRxiv · Aug 16, 2023 · PreprintImmunology
J. Tandel, K. A. Walzer, J. H. Byerly, B. Pinckston, D. P. Beiting, B. Striepen
This study identifies AP2-F as essential for oocyst shedding and transmission in Cryptosporidium parvum using a conditional gene ablation system.
bioRxiv · Nov 23, 2022 · PreprintMicrobiology
D. Sparvoli, J. Delabre, D. M. Penarete-Vargas, S. Kumar Mageswaran, L. M. Tsypin, J. Heckendorn, L. Theveny, M. Maynadier, M. Mendonca Cova, L. Berry-Sterkers, A. Guerin, J.-F. Dubremetz, S. Urbach, B. Striepen, A. P. Turkewitz, , M. LEBRUN
The paper identifies CRMPs as a complex involved in rhoptry exocytosis and invasion in Toxoplasma, acting as a host-molecular sensor.
bioRxiv · Feb 25, 2022 · PreprintCell Biology
E. D. English, A. Guerin, J. Tandel, B. Striepen
This study uses live imaging to reveal that Cryptosporidium parvum directly develops male and female gametes from type one meronts without a distinct intermediate stage.
bioRxiv · Dec 7, 2021 · PreprintMicrobiology
A. R. Gibson, A. Sateriale, J. E. Dumaine, J. B. Engiles, J. A. Gullicksrud, K. ODea, J. G. Doench, D. P. Beiting, C. A. Hunter, B. Striepen
This paper identifies a type III interferon response to Cryptosporidium requiring TLR3-dependent recognition, which protects against infection in mice.
bioRxiv · Oct 6, 2021Microbiology
J. E. Dumaine, A. Sateriale, A. R. Gibson, A. G. Reddy, J. A. Gullicksrud, E. N. Hunter, J. T. Clark, B. Striepen
This study identifies a Cryptosporidium secretion system that exports proteins into infected cells, triggering ER stress and contributing to pathogenesis.
bioRxiv · Jun 4, 2021Microbiology
J. Gullicksrud, A. Sateriale, J. B. Engiles, A. Gibson, S. Shaw, Z. Hutchins, L. Martin, D. A. Christian, G. A. Taylor, M. Yamamoto, D. P. Beiting, B. Striepen, C. Hunter
This study shows enterocytes promote ILC production of IFN-gamma, which restricts Cryptosporidium growth by acting on enterocytes themselves.
bioRxiv · Mar 13, 2021Immunology
A. Florentin, D. W. Cobb, J. D. Fishburn, M. J. Cipriano, P. S. Kim, M. A. Fierro, B. Striepen, V. Muralidharan
This paper identifies PfClpC as an essential apicoplast-targeted chaperone in Plasmodium falciparum, showing its role in maintaining apicoplast integrity and parasite viability.
bioRxiv · Jun 20, 2017Microbiology