Author

P. R. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Khromykh· 3 shared D. Watterson· 3 shared N. Modhiran· 3 shared A. A. Amarilla· 2 shared A. Isaacs· 2 shared B. Liang· 2 shared A. Amarilla· 1 shared A. Azuar· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersMicrobiology

A. A. Khromykh

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An alpaca-derived nanobody neutralizes the SARS-CoV-2 omicron variant

N. Modhiran, S. M. Lauer, A. A. Amarilla, P. Hewins, S. I. L. van den Broek, Y. S. Low, N. Thakur, B. Liang, G. V. Nieto, J. Jung, D. Paramitha, A. Isaacs, J. de Sng, D. Song, J. Jorgensen, , D. Watterson

This paper identifies a nanobody that effectively neutralizes the SARS-CoV-2 Omicron variants BA.1 and BA.2, showing high affinity and pre-clinical promise.

bioRxiv · Dec 27, 2022 · PreprintMicrobiology

Complete protection by a single dose skin patch delivered SARS-CoV-2 spike vaccine

C. L. D. McMillan, J. J. Y. Choo, A. Idris, A. Supramaniam, N. Modhiran, A. A. Amarilla, A. Isaacs, S. T. M. Cheung, B. Liang, H. Bielefeldt-Ohmann, A. Azuar, D. Acharya, G. Kelly, G. J. P. Fernando, M. J. Landsberg, , D. A. Muller

A single dose of a SARS-CoV-2 spike vaccine delivered via a high-density microarray patch provides complete protection against a lethal virus challenge.

bioRxiv · May 30, 2021Microbiology

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

S. E. Guimond, C. J. Mycroft-West, N. S. Gandhi, J. A. Tree, T. T. Le, C. M. Spalluto, M. V. Humbert, K. R. Buttigieg, N. Coombes, M. J. Elmore, K. Nystrom, J. Said, Y. X. Setoh, A. Amarilla, N. Modhiran, , J. E. Turnbull

This paper shows that pixatimod inhibits SARS-CoV-2 by disrupting the Spike-ACE2 interaction, demonstrating its potential as an anti-COVID-19 therapeutic.

bioRxiv · Jun 24, 2020Microbiology