Author

A. J. Bass

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Apffel· 1 shared A. D'Andrea· 1 shared A. Gonzalez· 1 shared A. Jones· 1 shared A. Nagaraja· 1 shared A. Tserniak· 1 shared B. Gaeta· 1 shared C. Marquis· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Apffel

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Author profile →

2 papers

Recent·Most cited

Selective vulnerability of aneuploid human cancer cells to inhibition of the spindle assembly checkpoint

Y. Cohen-Sharir, J. M. McFarland, M. Abdusamad, C. Marquis, H. Tang, M. R. Ippolito, S. V. Bernhard, K. Laue, H. L. Malaby, A. Jones, M. Kazachkova, N. Lyons, A. Nagaraja, A. J. Bass, R. Beroukhim, , U. Ben-David

This study identifies aneuploid cancer cells as more vulnerable to spindle assembly checkpoint (SAC) inhibition and explores the underlying mechanisms.

bioRxiv · Jun 18, 2020Cancer Biology

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

E. Chan, T. Shibue, J. McFarland, B. Gaeta, J. McPartlan, M. Ghandi, J. B. Liu, J.-B. Lazaro, N. Dumont, A. Gonzalez, A. Apffel, S. O. Ali, L. Leung, E. Roberts, E. Rizvochenko, , A. J. Bass

The paper identifies WRN helicase as a synthetic lethal target in microsatellite unstable cancers through CRISPR/Cas9 and RNAi screens, showing its essentiality in MSI cell lines.

bioRxiv · Dec 21, 2018Cancer Biology