Author

A. R. Pepper

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Bautista· 1 shared A. F. Spigelman· 1 shared C. C. Anderson· 1 shared C. Castro· 1 shared E. Ampofo· 1 shared G. S. Korbutt· 1 shared H. Lin· 1 shared J. Lin· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. Bautista

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Long-term survival and induction of operational tolerance to murine islet allografts through the co-transplantation of cyclosporine A eluting microparticles

P. Kuppan, J. Wong, S. Kelly, J. Lin, J. Worton, C. Castro, J. Paramor, K. Seeberger, C. C. Anderson, G. S. Korbutt, A. R. Pepper

This study shows that localized cyclosporine A delivery via microparticles combined with CTLA4-Ig reduces islet allograft rejection and induces operational tolerance in mice.

bioRxiv · Feb 14, 2023 · PreprintImmunology

β-cell responses to high fat feeding: A role and mechanism for redox sensing by SENP1

H. Lin, K. Suzuki, N. Smith, X. Li, L. Nalbach, S. Fuentes, A. F. Spigelman, X.-Q. Dai, A. Bautista, M. Ferdaoussi, S. Aggarwal, A. R. Pepper, L. P. Roma, E. Ampofo, W.-h. Li, P. E. MacDonald

This study identifies SENP1's role in β-cell redox sensing during high-fat feeding, showing its requirement for enhanced exocytosis and glucose intolerance.

bioRxiv · Apr 5, 2022Cell Biology