β-cell responses to high fat feeding: A role and mechanism for redox sensing by SENP1
H. Lin, K. Suzuki, N. Smith, X. Li, L. Nalbach, S. Fuentes, A. F. Spigelman, X.-Q. Dai, A. Bautista, M. Ferdaoussi, S. Aggarwal, A. R. Pepper, L. P. Roma, E. Ampofo, W.-h. Li, P. E. MacDonald
This study identifies SENP1's role in β-cell redox sensing during high-fat feeding, showing its requirement for enhanced exocytosis and glucose intolerance.
bioRxiv · Apr 5, 2022Cell Biology