Author

M. Ferdaoussi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. F. Spigelman· 3 shared N. Smith· 3 shared P. E. MacDonald· 3 shared A. Bautista· 2 shared H. Lin· 2 shared J. E. Manning Fox· 2 shared K. Suzuki· 2 shared A. Jha· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersPhysiology

A. F. Spigelman

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Author profile →

3 papers

Recent·Most cited

Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding

T. A. Alghamdi, N. A. J. Krentz, N. Smith, A. F. Spigelman, V. Rajesh, A. Jha, M. Ferdaoussi, J. E. Manning Fox, H. Sun, Z. Sun, A. L. Gloyn, P. E. MacDonald

This study shows that Zmiz1 is essential for β-cell function and mass expansion in response to high fat feeding, linking its loss to diabetes.

bioRxiv · May 18, 2022Physiology

β-cell responses to high fat feeding: A role and mechanism for redox sensing by SENP1

H. Lin, K. Suzuki, N. Smith, X. Li, L. Nalbach, S. Fuentes, A. F. Spigelman, X.-Q. Dai, A. Bautista, M. Ferdaoussi, S. Aggarwal, A. R. Pepper, L. P. Roma, E. Ampofo, W.-h. Li, P. E. MacDonald

This study identifies SENP1's role in β-cell redox sensing during high-fat feeding, showing its requirement for enhanced exocytosis and glucose intolerance.

bioRxiv · Apr 5, 2022Cell Biology

β-cell SENP1 facilitates responsiveness to incretins and limits oral glucose intolerance in high fat fed mice

H. Lin, N. Smith, A. F. Spigelman, K. Suzuki, M. Ferdaoussi, Y. Jin, A. Bautista, Y. W. Wang, J. E. Manning Fox, J. Buteau, P. E. MacDonald

This study shows that β-cell SENP1 improves insulin secretion in response to incretins and reduces oral glucose intolerance in high-fat-fed mice.

bioRxiv · Nov 30, 2020Physiology