Author

E. Ampofo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Approach:statistical model· 2

Frequent Co-Authors

B. Morgan· 2 shared L. P. Roma· 2 shared M. W. Laschke· 2 shared A. Bautista· 1 shared A. Diederich· 1 shared A. F. Spigelman· 1 shared A. G. Amaral· 1 shared A. Lotfinia· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersPhysiology

B. Morgan

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pancreatic islets undergo functional and morphological adaptation during development of Barth Syndrome

C. Carlein, M. D. Hoffmann, A. G. Amaral, C. Bickelmann, A. Lotfinia, L.-A. de Selliers, J. Audouze-Chaud, S. Wrublewsky, M. A. Lauterbach, K. von der Malsburg, M. van der Laan, M. Bozem, M. Hoth, P. Gilon, M. Ravier, , L. Prates Roma

The paper investigates how defective cardiolipin remodeling in Barth Syndrome affects pancreatic islet function and metabolism, finding improved glucose tolerance and compensatory metabolic adaptations in a mouse model.

bioRxiv · Jun 28, 2024 · PreprintPhysiology

The NAPstar family of NADP redox state sensors highlights glutathione as the primary mediator of anti-oxidative electron flux

M. Scherschel, J.-O. Niemeier, L. Jacobs, M. Hoffmann, A. Diederich, C. Bell, P. Hoehne, S. Raetz, J. Kroll, J. Steinbeck, S. Lichtenauer, J. Multhoff, J. Zimmermann, T. Sadhanasatish, R. A. Rothemann, , B. Morgan

The paper introduces NAPstar biosensors to measure NADP redox states and finds glutathione mediates anti-oxidative electron flux across eukaryotes.

bioRxiv · Feb 14, 2024 · PreprintBiochemistry

β-cell responses to high fat feeding: A role and mechanism for redox sensing by SENP1

H. Lin, K. Suzuki, N. Smith, X. Li, L. Nalbach, S. Fuentes, A. F. Spigelman, X.-Q. Dai, A. Bautista, M. Ferdaoussi, S. Aggarwal, A. R. Pepper, L. P. Roma, E. Ampofo, W.-h. Li, P. E. MacDonald

This study identifies SENP1's role in β-cell redox sensing during high-fat feeding, showing its requirement for enhanced exocytosis and glucose intolerance.

bioRxiv · Apr 5, 2022Cell Biology

Suppression of endothelial miR-22-3p mediates non-small cell lung cancer cell-induced angiogenesis

Y. Gu, G. Pais, V. Becker, C. Körbel, E. Ampofo, E. Ebert, J. Hohneck, N. Ludwig, E. Meese, R. M. Bohle, Y. Zhao, M. D. Menger, M. W. Laschke

The paper shows that reduced endothelial miR-22-3p in NSCLC tissues promotes angiogenesis by inhibiting SIRT1 and FGFR1, leading to AKT/mTOR inactivation and tumor growth.

bioRxiv · Apr 4, 2021Cancer Biology