Author

A. Savarino

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:metabolomics· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

B. Lucic· 2 shared I. L. Shytaj· 2 shared M. Lusic· 2 shared A. R. Goldman· 1 shared A. Singh· 1 shared A. T. Ayoub· 1 shared C. J. Neufeldt· 1 shared D. Alvarez-Carbonell· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

B. Lucic

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The FDA-approved drug cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication

I. L. Shytaj, M. Fares, B. Lucic, L. Gallucci, M. M. Tolba, L. Zimmermann, A. T. Ayoub, M. Cortese, C. J. Neufeldt, V. Laketa, P. Chlanda, O. T. Fackler, S. Boulant, R. Bartenschlager, M. Stanifer, , M. Lusic

This study shows that cobicistat synergizes with remdesivir to inhibit SARS-CoV-2 replication in cell lines and organoids, reducing viral replication to levels comparable to uninfected cells.

bioRxiv · Mar 9, 2021Microbiology

Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress

I. L. Shytaj, F. A. Procopio, M. Tarek, I. Carlon-Andres, H.-Y. Tang, A. R. Goldman, M. Munshi, M. Forcato, K. Leskov, F. Ye, B. Lucic, N. Cruz, A. Singh, S. Bicciato, S. Padilla-Parra, , A. Savarino

The paper shows that glycolysis downregulation is a hallmark of HIV-1 latency and that targeting antioxidant pathways can reactivate latent HIV-1.

bioRxiv · Dec 30, 2020Immunology