Author

N. Woodford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7 Epidemiology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 5 Approach:statistical model· 5 Approach:experimental assay· 4 Assay:whole-genome sequencing· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:variant calling· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

M. J. Ellington· 3 shared E. Jauneikaite· 2 shared S. Sriskandan· 2 shared A. A. van Belkum· 1 shared A. Coello Pelegrin· 1 shared A. D. G. Roberts· 1 shared A. E. Sheppard· 1 shared A. M. Karcher· 1 shared

Activity by Year

2016-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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3 shared papersMicrobiology

M. J. Ellington

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Author profile →

8 papers

Recent·Most cited

Emergence of optrA-mediated linezolid resistance in multiple lineages and plasmids of Enterococcus faecalis revealed by long read sequencing

M. P. McHugh, B. J. Parcell, K. A. Pettigrew, G. Toner, E. Khatamzas, A. M. Karcher, J. Walker, R. Weir, D. Meunier, K. L. Hopkins, N. Woodford, K. E. Templeton, S. H. Gillespie, M. T. Holden

This study identifies multiple optrA-mediated linezolid resistance variants in Enterococcus faecalis using long-read sequencing, showing genetic diversity and plasmid variability.

Microbiology · Feb 16, 2022Peer-reviewedMicrobiology

Diverse Genetic Determinants of Nitrofurantoin Resistance in UK Escherichia coli

Y. Wan, E. Mills, R. C. Y. Leung, A. Vieira, E. Jauneikaite, X. Zhi, N. J. Croucher, N. Woodford, M. J. Ellington, S. Sriskandan

This study identifies genetic factors causing nitrofurantoin resistance in UK E. coli, finding mutations and insertion sequences in nfsA and nfsB as major contributors.

Microbial Genomics · Dec 24, 2021Peer-reviewedMicrobiology

Effective in-vitro inactivation of SARS-CoV-2 by commercially available mouthwashes

K. Davies, H. Buczkowski, S. R. Welch, N. Green, D. Mawer, N. Woodford, A. D. G. Roberts, P. Nixon, D. Seymour, M. J. Killip

This study evaluates the in vitro efficacy of seven commercial mouthwashes against SARS-CoV-2, finding significant viral inactivation with certain formulations.

bioRxiv · Dec 2, 2020Microbiology

Reconciling the potentially irreconcilable? Genotypic and phenotypic amoxicillin-clavulanate resistance in Escherichia coli

T. J. Davies, N. Stoesser, A. E. Sheppard, M. Abuoun, P. W. Fowler, J. Swann, P. Quan, D. Griffiths, A. Vaughan, M. Morgan, H. T. T. Phan, K. J. Jeffery, M. Andersson, M. Ellington, O. Ekelund, , A. S. Walker

This study shows that amoxicillin-clavulanate resistance in E. coli is quantitative, not binary, and that WGS-based predictions outperform traditional phenotyping methods.

bioRxiv · Feb 6, 2020Microbiology

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: An inter-laboratory study

R. M. Doyle, D. M. O'Sullivan, S. D. Aller, S. Bruchmann, T. G. Clark, A. Coello Pelegrin, M. Cormican, E. Diez Benavente, M. J. Ellington, E. McGrath, Y. Motro, T. Phuong Thuy Nguyen, J. Phelan, L. P. Shaw, R. A. Stabler, , K. A. Harris

This study evaluates the reproducibility of antimicrobial resistance predictions from whole-genome sequencing data across different laboratories and identifies factors contributing to discordant results.

Microbial Genomics · Feb 1, 2020Peer-reviewedMicrobiology

Diversity of Escherichia coli from the enteric microbiota in patients with Escherichia coli bacteraemia

M. Mosavie, O. Blandy, E. Jauneikaite, I. Caldas, M. J. Ellington, N. Woodford, S. Sriskandan

This study compares the genetic diversity of E. coli in the gut microbiota of patients with E. coli bacteraemia versus other groups, finding reduced diversity in bacteraemia patients.

bioRxiv · Feb 27, 2019Microbiology

Different impacts of naturally occurring variants of the globally disseminated carbapenemase-encoding plasmid pKpQIL on the biology of host strains

H. T. H. Saw, M. Webber, N. Woodford, L. J. V. Piddock

This study compares the host range and fitness impacts of two variants of the pKpQIL plasmid in different bacterial hosts.

bioRxiv · Dec 13, 2018 · PreprintMicrobiology

Potential impact of novel diagnostics and treatments on the burden of antibiotic resistant in Escherichia coli

Pierre Nouvellet, J.V. Robotham, N.R. Naylor, N. Woodford, Neil M. Ferguson

The paper estimates the burden of E. coli bloodstream infections in Europe and assesses how novel diagnostics and treatments could reduce mortality and hospital stays.

bioRxiv · May 13, 2016 · PreprintEpidemiology