Author

Hairi Li

University of California San Diego

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:ATAC-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:rat· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

Abraham A. PalmeriD· 2 shared Francesca TeleseiD· 2 shared Giordano de GuglielmoiD· 2 shared Jiayu CheniD· 2 shared Lieselot L. G. CarretteiD· 2 shared Olivier GeorgeiD· 2 shared Xiang‐Dong FuiD· 2 shared Aaron J. Ho· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersGenomics

Abraham A. PalmerORCID

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4 papers

Recent·Most cited

Cocaine addiction-like behaviors are associated with long-term changes in gene regulation, energy metabolism, and GABAergic inhibition within the amygdala

Jessica Zhou, Giordano de Guglielmo, Aaron J. Ho, Marsida Kallupi, Narayan Prasad Pokhrel, Hairi Li, Apurva S. Chitre, Daniel B. Munro, Pejman Mohammadi, Lieselot L. G. Carrette, Olivier George, Abraham A. Palmer, Graham McVicker, Francesca Telese

The paper identifies cell type-specific gene regulatory changes in the amygdala of rats with varying cocaine addiction-like behaviors, linking them to energy metabolism, GABAergic inhibition, and chromatin accessibility.

bioRxiv · Sep 8, 2022 · PreprintGenomics

Glucocorticoid Receptor-Regulated Enhancers Play a Central Role in the Gene Regulatory Networks Underlying Drug Addiction

Sascha H. C. Duttke, Patricia Montilla‐Perez, Max W. Chang, Hairi Li, Hao Chen, Lieselot L. G. Carrette, Giordano de Guglielmo, Olivier George, Abraham A. Palmer, Christopher W. Benner, Francesca Telese

The paper investigates how drug exposure alters gene regulatory networks in the brain using multi-omics approaches, identifying enhancer repression and transcription factor involvement in addiction-related behaviors.

Frontiers in Neuroscience · May 16, 2022Peer-reviewedNeuroscience

Systematic Evaluation of Different R-loop Mapping Methods: Achieving Consensus, Resolving Discrepancies and Uncovering Distinct Types of RNA:DNA Hybrids

Jiayu Chen, Do‐Hwan Lim, Liang Chen, Yongli Zhou, Fangliang Zhang, Changwei Shao, Xuan Zhang, Hairi Li, Dong Wang, Dong‐Er Zhang, Xiang‐Dong Fu

The paper evaluates eight R-loop mapping technologies, identifies biases and artifacts, and classifies R-loops into two distinct types based on RPA binding patterns.

bioRxiv · Feb 18, 2022 · PreprintGenomics

A Large-Scale Binding and Functional Map of Human RNA Binding Proteins

Eric L. Van Nostrand, Peter Freese, Henry Pratt, Xiaofeng Wang, Xintao Wei, Rui Xiao, Steven M. Blue, Jiayu Chen, Neal A. L. Cody, Daniel Dominguez, Sara Olson, Balaji Sundararaman, Lijun Zhan, Cassandra A Bazile, Louis Philip Benoit Bouvrette, , Gene Wei-Ming Yeo

The paper maps and characterizes RNA elements recognized by human RNA binding proteins in K562 and HepG2 cells, expanding the catalog of functional elements in the human genome.

Nature · Jul 29, 2020Peer-reviewedGenomics