Author

Sarah E. Flannery

University of OxfordORCID 0000-0002-6580-5665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Ashwin JainarayananiD· 2 shared Jesusa CaperaiD· 2 shared Michael Loran DustiniD· 2 shared Román FischeriD· 2 shared Salvatore ValvoiD· 2 shared A.P. TurnbulliD· 1 shared Adán Pinto-FernándeziD· 1 shared Agathe Bernand· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

Ashwin JainarayananORCID

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Author profile →

3 papers

Recent·Most cited

Synaptic synergy of T cell receptor and interleukin 2 receptor in CD8+ T cells

Jesusa Capera, María Navarro‐Pérez, Ashwin Jainarayanan, Salvatore Valvo, Lina Chen, Panyu Fei, Sarah E. Flannery, Román Fischer, Sašo Čemerski, Simon Low, Steven N. Quayle, Raymond J. Moniz, Anish Suri, Michael Loran Dustin

The paper shows that TCR and IL2 receptor signaling synergize at the immunological synapse of CD8+ T cells, enhancing T-T synapse formation and function.

Nature Communications · Oct 7, 2026Peer-reviewedImmunology

Isolation of functional supramolecular attack particles (SMAPs)

Ashwin Jainarayanan, Vineethkrishna Chandrasekar, Vinnycius Pereira Almeida, Marcus A. Widdess, Claire C. Staton, Agathe Bernand, Veronika Pfannenstill, Sarah E. Flannery, Helena Watson, Amanda Wicki, Orthi Onupom, Mirudula Elanchezhian, Jesusa Capera, Lina Chen, Salvatore Valvo, , Michael Loran Dustin

This paper develops a method to isolate and characterize SMAPs from NK-92 cells, showing their cytotoxic activity against tumor cells in vitro and in vivo.

bioRxiv · Nov 10, 2025 · PreprintImmunology

obABPP-HT*: A Precision-Engineered Activity Proteomics Pipeline for the Streamlined Discovery of Deubiquitinase Inhibitors

Hannah B. L. Jones, Simeon D. Draganov, Sofia Schönbauer Huamán, Peter A. C. Wing, Chuong Nguyen, Zhu Liang, Julia Dörner, Jasper Lithgow, Emma J. Murphy, Alice Beard, Andrea Pierangelini, Jack W. Houghton, Mackenzie E. Robert, Sarah E. Flannery, Anthony Tumber, , Adán Pinto-Fernández

This paper introduces a high-throughput activity proteomics pipeline for discovering deubiquitinase inhibitors, identifying potent and selective inhibitors with minimal optimization.

bioRxiv · May 27, 2025 · PreprintBiochemistry