Author

Ahmed A. Abdou

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Assay:CUT&Tag· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marko JovanovićiD· 3 shared Benjamin J. BokoriD· 2 shared Darvesh GorheiD· 2 shared Ella Doron‐MandeliD· 2 shared Erica Wolin· 2 shared Lena Annika StreetiD· 2 shared Yanzhe MaiD· 2 shared Abdurrahman KeskiniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersSystems Biology

Marko JovanovićORCID

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3 papers

Recent·Most cited

SPIDR: a highly multiplexed method for mapping RNA-protein interactions uncovers a potential mechanism for selective translational suppression upon cellular stress

Erica Wolin, Jimmy K. Guo, Mario R. Blanco, Isabel Nadine Goronzy, Darvesh Gorhe, Wenzhao Dong, Andrew A. Perez, Abdurrahman Keskin, Elizabeth Valenzuela, Ahmed A. Abdou, Carl R. Urbinati, Ross T. Kaufhold, H. Tomas Rube, Jailson Brito Querido, Mitchell Guttman, Marko Jovanović

SPIDR is a high-throughput method for mapping RNA-protein interactions that identifies 4EBP1's role in selectively repressing mRNA translation under mTOR inhibition.

Cell · Jul 22, 2025Peer-reviewedSystems Biology

Large-scale map of RNA binding protein interactomes across the mRNA life-cycle

Lena Annika Street, Katherine L. Rothamel, Kristopher W. Brannan, Wenhao Jin, Benjamin J. Bokor, Kevin D. Dong, Kevin Rhine, Assael A. Madrigal, Norah Al-Azzam, Jenny Kim Kim, Yanzhe Ma, Darvesh Gorhe, Ahmed A. Abdou, Erica Wolin, Orel Mizrahi, , Gene Wei-Ming Yeo

The paper constructs an RNA-aware RBP-centric PPI map across the mRNA life-cycle, revealing 20,359 novel interactions and showing 73% are RNA-dependent.

Molecular Cell · Sep 19, 2024Peer-reviewedSystems Biology

A Multiplexed SEC-MS Approach to Systematically Study the Interplay Between Protein Assembly-States and Phosphorylation Events

Ella Doron‐Mandel, Benjamin J. Bokor, Yanzhe Ma, Lena Annika Street, Lauren C. Tang, Ahmed A. Abdou, Neel H. Shah, George Rosenberger, Marko Jovanović

The paper introduces SEC-MX, a method to simultaneously study protein assembly-states and phosphorylation events, and demonstrates its application in HEK293 and HCT116 cells.

bioRxiv · Jan 12, 2023 · PreprintMolecular Biology