DNA methylation outlier burden, health and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.
Anne Seeboth, Daniel L. McCartney, Yunzhang Wang, Robert Francis Hillary, Anna J. Stevenson, Rosie May Walker, Archie I Campbell, Kathryn Louise Evans, Andrew Mark McIntosh, Sara Hägg, Ian J. Deary, Riccardo Emilio Marioni
This study examines DNA methylation outlier burden as a marker of biological age and finds it increases with age but is not strongly linked to health outcomes or survival.
Clinical Epigenetics · Mar 26, 2020Peer-reviewedGenetic & Genomic Medicine